ArticleBMC genomics2014
Genome-wide characterization and comparative analysis of R2R3-MYB transcription factors shows the complexity of MYB-associated regulatory networks in Salvia miltiorrhiza.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed, 132 citations in OpenAlex.
- Genome-wide identification of MYB transcription factors in Rheum officinale Baill. and their responses to UV-B and MeJA treatment.BMC plant biology · 2026Article
- Systematic characterization of the R2R3-MYB family in Lithospermum erythrorhizon and regulatory mechanisms of LeMYB1 in shikonin biosynthesis.BMC plant biology · 2026Article
- Genome-Wide Identification and Transcriptomic Analysis ofInternational journal of molecular sciences · 2026Article
- Comprehensive analysis of VOZ proteins in sweet potato and related species reveals their evolutionary dynamics and responses to abiotic stresses.Frontiers in plant science · 2026Article
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- SmCSN5 is a synergist in the transcription factor SmMYB36-mediated biosynthesis of tanshinones and phenolic acids inHorticulture research · 2025Article
- Transgene-free CRISPR/Cas9-mediated gene editing through protoplast-to-plant regeneration enhances active compounds in Salvia miltiorrhiza.Plant biotechnology journal · 2024Article
- The MYB family and their response to abiotic stress in ginger (Zingiber officinale Roscoe).BMC genomics · 2024Article
- Genome-Wide Identification and Functional Analysis ofInternational journal of molecular sciences · 2024Article
- The Smi-miR858a-Horticulture research · 2024Article
- Phenolic Acids and Flavonoids Play Important Roles in Flower Bud Differentiation inInternational journal of molecular sciences · 2023Article
- Simultaneous Promotion of Salt Tolerance and Phenolic Acid Biosynthesis inInternational journal of molecular sciences · 2023Article
- A Comprehensive Review of the Key Characteristics of the GenusIranian journal of biotechnology · 2023Review
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- Transcriptome analysis of three medicinal plants of the genusFrontiers in plant science · 2023Article
- Biosynthetic regulatory network of flavonoid metabolites in stems and leaves of Salvia miltiorrhiza.Scientific reports · 2022Article
- SmMYB4 Is a R2R3-MYB Transcriptional Repressor Regulating the Biosynthesis of Phenolic Acids and Tanshinones inMetabolites · 2022Article
- Systematic Analysis and Functional Characterization of R2R3-MYB Genes inInternational journal of molecular sciences · 2022Article
- Article
8 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMYB is the largest plant transcription factor gene family playing vital roles in plant growth and development. However, it has not been systematically studied in Salvia miltiorrhiza, an economically important medicinal plant.
resultsHere we report the genome-wide identification and characterization of 110 R2R3-MYBs, the largest subfamily of MYBs in S. miltiorrhiza. The MYB domain and other motifs of SmMYBs are largely conserved with Arabidopsis AtMYBs, whereas the divergence of SmMYBs and AtMYBs also exists, suggesting the conservation and diversity of plant MYBs. SmMYBs and AtMYBs may be classified into 37 subgroups, of which 31 include proteins from S. miltiorrhiza and Arabidopsis, whereas 6 are specific to a species, indicating that the majority of MYBs play conserved roles, while others may exhibit species-specialized functions. SmMYBs are differentially expressed in various tissues of S. miltiorrhiza. The expression profiles are largely consistent with known functions of their Arabidopsis counterparts. The expression of a subset of SmMYBs is regulated by microRNAs, such as miR159, miR319, miR828 and miR858. Based on functional conservation of MYBs in a subgroup, SmMYBs potentially involved in the biosynthesis of bioactive compounds were identified.
conclusionsA total of 110 R2R3-MYBs were identified and analyzed. The results suggest the complexity of MYB-mediated regulatory networks in S. miltiorrhiza and provide a foundation for understanding the regulatory mechanism of SmMYBs.
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