ArticleThe American journal on addictions
High levels of opioid analgesic co-prescription among methadone maintenance treatment clients in British Columbia, Canada: results from a population-level retrospective cohort study.
Article in The American journal on addictions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Benzodiazepine Use Among Patients Receiving Methadone Maintenance Treatment: A Descriptive Study.Drug design, development and therapy · 2026Article
- Opioid withdrawal produces sex-specific effects on fentanyl-vs.-food choice and mesolimbic transcription.Biological psychiatry global open science · 2021Article
- Cohort profile: The provincial substance use disorder cohort in British Columbia, Canada.International journal of epidemiology · 2021Article
- The Abuse Characteristics of Amphetamine-Type Stimulants in Patients Receiving Methadone Maintenance Treatment and Buprenorphine Maintenance Treatment.Drug design, development and therapy · 2021Article
- Gender Differences in Patterns and Correlates of Continued Substance Use among Patients in Methadone Maintenance Treatment.Substance use & misuse · 2021Article
- Dyadic associations between relationship quality and risk of opioid use among couples receiving methadone for opioid use disorder.Drug and alcohol dependence · 2021Article
- Non-disclosure of drug use in outpatient health care settings: Findings from a prospective cohort study in Vancouver, Canada.The International journal on drug policy · 2020Article
- Article
- Too much or too little opioids to patients receiving opioid agonist therapy in Norway (2013-2017): a prospective cohort study.BMC health services research · 2020Article
- Chronic Pain Opioid-Maintained Patients Receive Less Analgesic Opioid Prescriptions.Frontiers in psychiatry · 2018Article
- Inability to access health and social services associated with mental health among people who inject drugs in a Canadian setting.Drug and alcohol dependence · 2016Article
- Seeking prescription opioids from physicians for nonmedical use among people who inject drugs in a Canadian setting.The American journal on addictions · 2016Observational
- Characterizing pain and associated coping strategies in methadone and buprenorphine-maintained patients.Drug and alcohol dependence · 2015Article
- Designing a Pharmacist Opioid Safety and Intervention Tool.The Canadian journal of hospital pharmacyArticle
- Prevalence of Substance Use in an HIV Primary Care Safety Net Clinic: A Call for Screening.The Journal of the Association of Nurses in AIDS Care : JANACArticle
- Characteristics of methadone maintenance treatment patients prescribed opioid analgesics.Substance abuseArticle
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesThe non-medical use of prescription opioids (PO) has increased dramatically in North America. Special consideration for PO prescription is required for individuals in methadone maintenance treatment (MMT). Our objective is to describe the prevalence and correlates of PO use among British Columbia (BC) MMT clients from 1996 to 2007.
methodsThis study was based on a linked, population-level medication dispensation database. All individuals receiving 30 days of continuous MMT for opioid dependence were included in the study. Key measurements included the proportion of clients receiving >7 days of a PO other than methadone during MMT from 1996 to 2007. Factors independently associated with PO co-prescription during MMT were assessed using generalized linear mixed effects regression.
results16,248 individuals with 27,919 MMT episodes at least 30 days in duration were identified for the study period. Among them, 5,552 individuals (34.2%) received a total of 290,543 PO co-prescriptions during MMT. The majority (74.3%) of all PO dispensations >7 days originated from non-MMT physicians. The number of PO prescriptions per person-year nearly doubled between 1996 and 2006, driven by increases in morphine, hydromorphone and oxycodone dispensations. PO co-prescription was positively associated with female gender, older age, higher levels of medical co-morbidity as well as higher MMT dosage, adherence, and retention. CONCLUSION AND SCIENTIFIC SIGNIFICANCE: A large proportion of MMT clients in BC received co-occurring PO prescriptions, often from physicians and pharmacies not delivering MMT. Experimental evidence for the treatment of pain in MMT clients is required to guide clinical practice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.