Evidence map›Paper›PMID 24724097›Full record

ReviewBioMed research international2014

Designs and techniques that improve the pullout strength of pedicle screws in osteoporotic vertebrae: current status.

Thomas M Shea, Jake Laun, Sabrina A Gonzalez-Blohm, James J Doulgeris, William E Lee, Kamran Aghayev, Frank D Vrionis

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Trial
  2. A comprehensive review of biomechanical factors influencing pedicle screw fixation strength and the critical role of artificial intelligence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Biomechanical comparison of pedicle screw fixation strength between traditional trajectory and the single and double endplates penetrating screw trajectories in cadaver spine.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Satisfactory 2-year outcome of minimal invasive hybrid stabilization with double treated screws for unstable osteoporotic spinal fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  15. Article
  16. Article
  17. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas M SheaH. Lee Moffitt Cancer Center & Research Institute, Neuro-Oncology Department, Tampa, FL 33612, USA ; Department of Chemical & Biomedical Engineering, University of South Florida, Tampa, FL 33620, USA.
Jake LaunMorsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.
Sabrina A Gonzalez-BlohmH. Lee Moffitt Cancer Center & Research Institute, Neuro-Oncology Department, Tampa, FL 33612, USA.
James J DoulgerisH. Lee Moffitt Cancer Center & Research Institute, Neuro-Oncology Department, Tampa, FL 33612, USA ; Department of Mechanical Engineering, University of South Florida, Tampa, FL 33620, USA.
William E LeeDepartment of Mechanical Engineering, University of South Florida, Tampa, FL 33620, USA.
Kamran AghayevH. Lee Moffitt Cancer Center & Research Institute, Neuro-Oncology Department, Tampa, FL 33612, USA ; Departments of Neurosurgery and Orthopedics, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.ORCID 0000-0002-5085-8115
Frank D VrionisH. Lee Moffitt Cancer Center & Research Institute, Neuro-Oncology Department, Tampa, FL 33612, USA ; Departments of Neurosurgery and Orthopedics, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a medical condition affecting men and women of different age groups and populations. The compromised bone quality caused by this disease represents an important challenge when a surgical procedure (e.g., spinal fusion) is needed after failure of conservative treatments. Different pedicle screw designs and instrumentation techniques have been explored to enhance spinal device fixation in bone of compromised quality. These include alterations of screw thread design, optimization of pilot hole size for non-self-tapping screws, modification of the implant's trajectory, and bone cement augmentation. While the true benefits and limitations of any procedure may not be realized until they are observed in a clinical setting, axial pullout tests, due in large part to their reproducibility and ease of execution, are commonly used to estimate the device's effectiveness by quantifying the change in force required to remove the screw from the body. The objective of this investigation is to provide an overview of the different pedicle screw designs and the associated surgical techniques either currently utilized or proposed to improve pullout strength in osteoporotic patients. Mechanical comparisons as well as potential advantages and disadvantages of each consideration are provided herein.

Indexed as

Bone ScrewsProsthesis DesignAnimalsFemaleHumansMaleOsteoporosisSpine

Identifiers

PMID24724097
PMCPMC3958762

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.