Trial reportBioMed research international2014
High-intensity interval training in patients with substance use disorder.
Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Aerobic Endurance Training in Patients With Drug Addiction
Effects of Core Stabilization Exercises on Pulmonary Functions, Respiratory Muscle Strength and Functional Capacity in Adolescents With Substance Use Disorder. A Randomized Controlled Study
Who cites it
35 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Effects of physical exercise on sleep quality in patients with psychiatric disorders: a systematic review and meta-analysis.BMC psychiatry · 2026Pooled it
- The effects of exercise interventions on substance-use outcomes: A meta-analytic and systematic review.Experimental and clinical psychopharmacology · 2025Pooled it
- The Impact of Physical Activity on Sleep in Alcohol Users: A Systematic Review.Addiction biology · 2025Pooled it
- Effect of physical exercise on the emotional and cognitive levels of patients with substance use disorder: a meta-analysis.Frontiers in psychology · 2024Pooled it
- Rates of compliance and adherence to high-intensity interval training: a systematic review and Meta-analyses.The international journal of behavioral nutrition and physical activity · 2023Pooled it
- Pooled it
- A Systematic Review of Exercise Intervention Program for People With Substance Use Disorder.Frontiers in psychiatry · 2022Pooled it
- Effects of High-Intensity Interval Training on Sleep: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- The Benefits of Physical Exercise on Mental Disorders and Quality of Life in Substance Use Disorders Patients. Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Short-Term (<8 wk) High-Intensity Interval Training in Diseased Cohorts.Medicine and science in sports and exercise · 2018Pooled it
- The effect of daily aerobic cycling exercise on cannabis withdrawal: An inpatient randomised controlled trial.Scientific reports · 2026Trial
- Transcranial direct current stimulation associated with physical exercise can help smokers to quit smoking: a randomized controlled trial.Scientific reports · 2025Trial
- Comparative effects of Health Qigong and closed motor exercise on the physical and mental health of female drug rehabilitation participants: a randomized controlled trial.BMC complementary medicine and therapies · 2025Trial
- Aerobic high-intensity interval training and maximal strength training in patients with unspecific musculoskeletal disorders improve V̇OEuropean journal of sport science · 2024Trial
- Psychological and endocannabinoid responses to aerobic exercise in substance use disorder patients.Substance abuse · 2021Trial
- Maximal strength training improves musculoskeletal health in amphetamine users in clinical treatment.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Trial
- Article
- Exercise Training Interventions as Therapeutic Approaches in Substance Use Disorder Treatment: A Scoping Review of Direct Clinical Outcomes and Implementation Strategies.Diseases (Basel, Switzerland) · 2026Review
- Impact of physical activity on sleep in adults recovering from substance use disorders: a protocol for an N-of-1 observational study.BMJ open · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with substance use disorder (SUD) suffer a higher risk of cardiovascular disease and other lifestyle diseases compared to the general population. High intensity training has been shown to effectively reduce this risk, and therefore we aimed to examine the feasibility and effect of such training in SUD patients in clinical treatment in the present study. 17 males and 7 females (32 ± 8 yr) in treatment were randomized to either a training group (TG), treadmill interval training in 4 × 4 minutes at 90-95% of maximal heart rate, 3 days a week for 8 weeks, or a conventional rehabilitation control group (CG). Baseline values for both groups combined at inclusion were 44 ± 8 (males) and 34 ± 9 (females) mL · min(-1) · kg(-1), respectively. 9/12 and 7/12 patients completed the TG and CG, respectively. Only the TG significantly improved (15 ± 7%) their maximal oxygen consumption (VO2max), from 42.3 ± 7.2 mL · min(-1) · kg(-1) at pretest to 48.7 ± 9.2 mL · min(-1) · kg(-1) at posttest. No between-group differences were observed in work economy, and level of insomnia (ISI) or anxiety and depression (HAD), but a significant within-group improvement in depression was apparent for the TG. High intensity training was feasible for SUD patients in treatment. This training form should be implemented as a part of the rehabilitation since it, in contrast to the conventional treatment, represents a risk reduction for cardiovascular disease and premature death.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.