Evidence map›Paper›PMID 24723894›Full record

ReviewFrontiers in psychiatry2014

Computational neuropsychiatry - schizophrenia as a cognitive brain network disorder.

Maria R Dauvermann, Heather C Whalley, André Schmidt, Graham L Lee, Liana Romaniuk, Neil Roberts, Eve C Johnstone, Stephen M Lawrie, Thomas W J Moorhead

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Maria R DauvermannDivision of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh , Edinburgh , UK.
Heather C WhalleyDivision of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh , Edinburgh , UK.
André SchmidtDepartment of Psychiatry, University of Basel , Basel , Switzerland ; Medical Image Analysis Center, University Hospital Basel , Basel , Switzerland.
Graham L LeeMcGovern Institute for Brain Research, Massachusetts Institute of Technology , Cambridge, MA , USA.
Liana RomaniukDivision of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh , Edinburgh , UK.
Neil RobertsClinical Research Imaging Centre, QMRI, University of Edinburgh , Edinburgh , UK.
Eve C JohnstoneDivision of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh , Edinburgh , UK.
Stephen M LawrieDivision of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh , Edinburgh , UK.
Thomas W J MoorheadDivision of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh , Edinburgh , UK.
Royal Edinburgh Hospital · GBMcGovern Institute for Brain Research · USThe Queen's Medical Research Institute · GBUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Computational modeling of functional brain networks in fMRI data has advanced the understanding of higher cognitive function. It is hypothesized that functional networks mediating higher cognitive processes are disrupted in people with schizophrenia. In this article, we review studies that applied measures of functional and effective connectivity to fMRI data during cognitive tasks, in particular working memory fMRI studies. We provide a conceptual summary of the main findings in fMRI data and their relationship with neurotransmitter systems, which are known to be altered in individuals with schizophrenia. We consider possible developments in computational neuropsychiatry, which are likely to further our understanding of how key functional networks are altered in schizophrenia.

Indexed as

cognitioncomputational neuropsychiatrydopaminedynamic causal modelingfMRIglutamateneurotransmitterschizophrenia

Identifiers

PMID24723894
PMCPMC3971172
OpenAlexW2085281949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.