ArticleTheScientificWorldJournal2014
Effects of traditional Chinese medicine Shuxuetong injection on random skin flap survival in rats.
Article in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 20 citations in OpenAlex.
- Shuxuetong injection simultaneously ameliorates dexamethasone-driven vascular calcification and osteoporosis.Experimental and therapeutic medicine · 2021Article
- Crocin enhances the viability of random pattern skin flaps: involvement of enhancing angiogenesis and inhibiting oxidative stress.American journal of translational research · 2020Article
- An injectable thermosensitive hydrogel for sustained release of apelin-13 to enhance flap survival in rat random skin flap.Journal of materials science. Materials in medicine · 2019Article
- The effects of local injection of exosomes derived from BMSCs on random skin flap in rats.American journal of translational research · 2019Article
- Peroneal artery perforator flap for the treatment of chronic lower extremity wounds.Journal of orthopaedic surgery and research · 2017Article
- Effects of diammonium glycyrrhizinate on random skin flap survival in rats: An experimental study.Biomedical reports · 2016Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA Shuxuetong injection is traditionally used in Chinese medicine to treat "blood stasis and stagnation" (yu xue yu zhi). We investigated the effect of such injection on the survival of random skin flaps.
methodsMcFarlane flaps were established in 60 rats divided into two groups. Postoperative celiac injections were given to both groups for 7 days. Shuxuetong was injected into the test group, and saline was injected into controls. On day 7, tissues were stained with H&E (hematoxylin-eosin) stain, immunohistochemically evaluated, and the expression levels of xanthine oxidase were determined.
resultThe mean area of flap survival in the test group was significantly higher than in controls. Expression of vascular endothelial growth factor and superoxide dismutase, and microvessel development, were markedly increased in the test group, and the malondialdehyde level was reduced.
conclusionShuxuetong promotes random skin flap survival.
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