ArticleGenome biology and evolution2014
Genome-wide analyses of a plant-specific LIM-domain gene family implicate its evolutionary role in plant diversification.
Article in Genome biology and evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 28 citations in OpenAlex.
- Harnessing genomics and transcriptomics to explore the genetic and molecular basis of abiotic stress tolerance in minor millets - a comprehensive review.Functional & integrative genomics · 2026Review
- Genome-wide identification and expression analysis of theFrontiers in plant science · 2025Article
- Genome Wide Identification and Characterization of LIM Domain Associated Gene Superfamily in Common Bean (International journal of genomics · 2025Article
- Genome-Wide Identification and Expression Analysis of theInternational journal of molecular sciences · 2024Article
- A genome‑wide approach to the systematic and comprehensive analysis of LIM gene family in sorghum (Sorghum bicolor L.).Genomics & informatics · 2023Article
- Comprehensive In Silico Characterization and Expression Pro-Filing of DA1/DAR Family Genes inGenes · 2022Article
- Genome-wide identification and expression analysis of the plant specific LIM genes in Gossypium arboreum under phytohormone, salt and pathogen stress.Scientific reports · 2021Article
- Genome-wide identification, characterization and expression analysis of the LIM transcription factor family in quinoa.Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Article
- The alcohol dehydrogenase gene family in sugarcane and its involvement in cold stress regulation.BMC genomics · 2020Article
- Genome-Wide Analysis ofInternational journal of molecular sciences · 2019Article
- Transcriptomic Evidence of Adaptive Evolution of the Epiphytic FernInternational journal of genomics · 2019Article
- Review
- Article
- Sequence and expression variations suggest an adaptive role for the DA1-like gene family in the evolution of soybeans.BMC plant biology · 2015Article
- Comprehensive Expression Profiling of Rice Tetraspanin Genes Reveals Diverse Roles During Development and Abiotic Stress.Frontiers in plant science · 2015Article
- Genome Wide Identification of LIM Genes in Cicer arietinum and Response of Ca-2LIMs in Development, Hormone and Pathogenic Stress.PloS one · 2015Article
- Identification and characterization of LIM gene family in Brassica rapa.BMC genomics · 2014Article
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Authors and funding
6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The Arabidopsis DA1 genes appear to have multiple functions in regulating organ size and abiotic stress response, but the biological roles of its closely related genes remain unknown. Evolutionary analyses might provide some clues to aid in an understanding of their functional diversification. In this work, we characterized the molecular evolution and expressional diversification of DA1-like genes. Surveying 354 sequenced genomes revealed 142 DA1-like genes only in plants, indicating plant-specificity of these genes. The DA1-like protein modular structure was composed of two UIMs (ubiquitin interaction motifs), one LIM-domain (from lin-11, isl-1, and mec-3), and a conserved C-terminal, and was distinguishable from the already defined three groups of LIM-domain proteins. We further found that the DA1-like genes diverged into Classes I and II at the ancestor of seed plants and acquired 13 clade-specific residues during their evolutionary history. Moreover, diverse intron size evolution was noted following the transition from size-expandable introns to minimal ones, accompanying the emergence and diversification of angiosperms. Functional diversification as it relates to gene expression was further investigated in soybean. Glycine max DA1 genes showed diverse tissues expression patterns during development and had substantially varied abiotic stress response expression. Thus, variations in the coding regions, intron size, and gene expression contributed to the functional diversification of this gene family. Our data suggest that the evolution of the DA1-like genes facilitated the development of diverse molecular and functional diversification patterns to accompany the successful radiation of plants into diverse environments during evolution.
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