Evidence map›Paper›PMID 24723565›Full record

ArticleNeuro-oncology2014

Incidence and relative survival of anaplastic astrocytomas.

Nicolas R Smoll, Brett Hamilton

Abstract read
In one paragraph

Article in Neuro-oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. The novel [RSC advances · 2026
    Article
  2. Article
  3. Updates on management of gliomas in the molecular age.World journal of clinical oncology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicolas R SmollDepartment of Medicine, Peninsula Health, Frankston, Victoria, Australia (N.R.S., B.H.).
Brett HamiltonDepartment of Medicine, Peninsula Health, Frankston, Victoria, Australia (N.R.S., B.H.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to investigate the relationship between age and the incidence and relative survival of anaplastic astrocytoma (AA).

methodsData from the Surveillance, Epidemiology and End Results database were used to identify 3202 patients with AA. These data were analyzed to assess incidence rates, relative survival, and the standardized mortality ratio across age groups. Time trends were modeled using delayed-entry modeling.

resultsThe overall incidence of AA was an age-adjusted rate of 3.5 per million person/years. The overall age-standardized 5- and 10-year relative survival rates of populations with AA were 23.6% and 15.1%, respectively. The overall standardized mortality ratio for the entire cohort was 46 (95% confidence interval: 45, 48).

conclusionsPatients with a diagnosis of AA are 46 times more likely to die than persons matched for age/sex/year of the general population. The effect of age on survival is present for only the first 2 years postdiagnosis. Measuring the effect of age on survival for populations with an AA is not amenable to using models with proportional hazards as an assumption because of the presence of a reverse fork-type interaction.

Indexed as

AdolescentAdultAgedAge FactorsAstrocytomaBrain NeoplasmsChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornKaplan-Meier EstimateMaleMiddle Agedanaplastic astrocytomabrain tumornonproportional hazardsrelative survivalstandardized mortality ratio

Identifiers

PMID24723565
PMCPMC4165416

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.