Evidence map›Paper›PMID 24723427›Full record

SynthesisThe Laryngoscope2015

The prevalence of bacterial infection in acute rhinosinusitis: a Systematic review and meta-analysis.

Stephanie S Smith, Elisabeth H Ference, Charlesnika T Evans, Bruce K Tan, Robert C Kern, Rakesh K Chandra

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Laryngoscope, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Cyclamen europaeum extract for acute sinusitis.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Guideline
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Hyaluronic Acid in Rhinology: Its Uses, Advantages and Drawbacks-A Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. In vitro detection of common rhinosinusitis bacteria by the eNose utilising differential mobility spectrometry.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Article
  18. Observational
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stephanie S SmithDepartment of Otolaryngology-Head and Neck Surgery, Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago; Department of Preventative Medicine, Northwestern University Feinberg School of Medicine, Chicago.
Elisabeth H Ference
Charlesnika T Evans
Bruce K Tan
Robert C Kern
Rakesh K Chandra
Northwestern University · US

Funding

Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisU19AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KERN, ROBERT C · 2014 to 2017
$7.9M
NRSA INSTITUTIONAL TRAINING GRANTT32HS000078 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HOLL, JANE LOUISE · 1998 to 2018
$5.6M
Role for B-cell mediated olfactory loss in Chronic Sinusitis with Nasal PolypsK23DC012067 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI TAN, BRUCE K · 2012 to 2016
$1.1M
AHRQ HHS T-32 HS 000078AHRQ HHS T32 HS000078NIAID NIH HHS U19 AI106683NIDCD NIH HHS 1K23DC012067NIDCD NIH HHS K23 DC012067
6 · The paper itself

Abstract

objectives/hypothesisTo systematically assess the prevalence of bacterial infection in adults with acute rhinosinusitis (ARS).

methodsElectronic databases were systematically searched for relevant studies published up to June 2012.

resultsTwenty-nine articles, evaluating a total of 9,595 patients with a clinical diagnosis of ARS, were included in the study. Of these, 14 (48%) studies required radiographic confirmation of sinusitis, one study (3%) required evidence of purulence, 10 studies (35%) required both for inclusion in the study population, and four studies (14%) required neither. The random effects model estimate of prevalence of bacterial growth on all cultures was 53.7% (CI 48.4%-59.0%), ranging from 52.5% (CI 46.7%-58.3%) in studies requiring radiographic confirmation of sinusitis to 61.1% (CI 54.0%-68.1%) in studies requiring neither radiographic evidence nor purulence on exam. Studies that obtained cultures from antral swab had a prevalence of bacterial growth of 61.0% (CI 54.7%-67.2%), whereas those utilizing endoscopic meatal sampling had a prevalence of 32.9% (CI 19.0%-46.8%).

conclusionsFew studies evaluate the recovery of bacteria via culture in adults with a diagnosis of ABRS or ARS based on clinical criteria alone. With radiographic and/or endoscopic confirmation, antral puncture and endoscopically guided cultures produce positive bacterial cultures in approximately one-half of patients. Opportunities exist to improve diagnostic accuracy for bacterial infection in ARS.

Indexed as

Acute DiseaseAdolescentAdultAgedBacterial InfectionsBacteriological TechniquesCross-Sectional StudiesEndoscopyFemaleHumansMaleMiddle AgedRadiographyRhinitisSinusitisYoung Adultacute rhinosinusitisantral puncturebacterial infectionendoscopic middle meatus culturemeta-analysisSystematic review

Identifiers

PMID24723427
PMCPMC4192102
OpenAlexW1503641150

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.