ReviewApplied biochemistry and biotechnology2014
Electrochemical sensing of cortisol: a recent update.
Review in Applied biochemistry and biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Article
- A Dual Biomarker Approach to Stress: Hair and Salivary Cortisol Measurement in Students via LC-MS/MS.Analytical science advances · 2025Article
- An in silico design method of a peptide bioreceptor for cortisol using molecular modelling techniques.Scientific reports · 2024Article
- Advances in electrochemical biosensor design for the detection of the stress biomarker cortisol.Analytical and bioanalytical chemistry · 2024Review
- Patient-Reported Impact of Symptoms in Spinal and Bulbar Muscular Atrophy.Neurology. Clinical practice · 2023Article
- Carbon Electrode Sensor for the Measurement of Cortisol with Fast-Scan Cyclic Voltammetry.Biosensors · 2023Article
- Advances in microfluidic chips based on islet hormone-sensing techniques.World journal of diabetes · 2023Review
- Nanostructured Cyclodextrin-Mediated Surface for Capacitive Determination of Cortisol in Multiple Biofluids.ACS applied materials & interfaces · 2022Article
- Recent research trends in voltammetric sensing platforms for hormones and their applications to human serum analyses.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2022Review
- Immunosensor for Assessing the Welfare of Trainee Guide Dogs.Biosensors · 2021Article
- Single-step label-free nanowell immunoassay accurately quantifies serum stress hormones within minutes.Science advances · 2021Article
- Toward Predicting Human Performance Outcomes From Wearable Technologies: A Computational Modeling Approach.Frontiers in physiology · 2021Article
- Extended gate field-effect-transistor for sensing cortisol stress hormone.Communications materials · 2021Article
- Validation of an Electrochemical Sensor to Detect Cortisol Responses to the Trier Social Stress Test.Neurobiology of stress · 2020Article
- Smart, soft contact lens for wireless immunosensing of cortisol.Science advances · 2020Article
- Identification of Suitable Biomarkers for Stress and Emotion Detection for Future Personal Affective Wearable Sensors.Biosensors · 2020Review
- Article
- Article
- Transitioning from acute to chronic pain: a simulation study of trajectories of low back pain.Journal of translational medicine · 2019Article
- Salivary Electrochemical Cortisol Biosensor Based on Tin Disulfide Nanoflakes.Nanoscale research letters · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
Psychological stress caused by everyday lifestyle contributes to health disparities experienced by individuals. It affects many biomarkers, but cortisol - "a steroid hormone" - is known as a potential biomarker for psychological stress detection. Abnormal levels of cortisol are indicative of conditions such as Cushing's syndrome Addison's disease, adrenal insufficiencies and more recently post-traumatic stress disorder (PTSD). Chromatographic techniques, which are traditionally used to detect cortisol, are a complex system requiring multistep extraction/purification. This limits its application for point-of-care (POC) detection of cortisol. However, electrochemical immunosensing of cortisol is a recent advancement towards POC application. This review highlights simple, low-cost, and label-free electrochemical immunosensing platforms which have been developed recently for sensitive and selective detection of cortisol in bio-fluids. Electrochemical detection is utilized for the detection of cortisol using Anti-Cortisol antibodies (Anti-Cab) covalently immobilized on nanostructures, such as self-assembled monolayer (SAM) and polymer composite, for POC integration of sensors. The observed information can be used as a prototype to understand behavioral changes in humans such as farmers and firefighters. Keeping the future directions and challenges in mind, the focus of the BioMEMS and Microsystems Research Group at Florida International University is on development of POC devices for immunosensing, integration of these devices with microfluidics, cross validation with existing technologies, and analysis of real sample.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.