ArticleAmerican journal of epidemiology2014
Physical activity across adulthood in relation to fat and lean body mass in early old age: findings from the Medical Research Council National Survey of Health and Development, 1946-2010.
Article in American journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02377037 (What is the Metabolic Cost of Sitting, Standing, and Sit/Stand Transitions? A Randomized Controlled Trial), which is not on this map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
What is the Metabolic Cost of Sitting, Standing, and Sit/Stand Transitions? A Randomized Controlled Trial
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Physical Activity Producing Low, but Not Medium or Higher, Vertical Impacts Is Inversely Related to BMI in Older Adults: Findings From a Multicohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018Pooled it
- Impact of dietary protein quantity on the non-dysbiotic human microbiome: a controlled feeding study.Scientific reports · 2026Trial
- Physical Activity Across Adulthood and Bone Health in Later Life: The 1946 British Birth Cohort.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019Trial
- Trial
- Changes in physical activity and diabetes risk after cancer diagnosis: a nationwide cohort study.Journal of cancer survivorship : research and practice · 2025Article
- Associations of Markers of Inflammatory Status and Adiposity with Bone Phenotype at Age 60-64 Years: Findings from the MRC National Survey of Health and Development.Calcified tissue international · 2025Article
- Association between lean body mass and osteoarthritis: a cross-sectional study from the NHANES 2007-2018.Scientific reports · 2025Article
- Diet quality from mid-life and body composition in older age: findings from a British birth cohort.The British journal of nutrition · 2025Article
- Physical activity assessment in rheumatoid arthritis: a 120-patient cross-sectional study.La Tunisie medicale · 2024Article
- Replacing sedentary time for physical activity: Does intensity matter for body composition in oldest-old adults?Journal of sports sciences · 2024Article
- The Relationship of Physical Activity and Dietary Quality with Android Fat Composition and Distribution in US Adults.Nutrients · 2022Article
- Validity and Relative Validity of Alternative Methods of Assessing Physical Activity in Epidemiologic Studies: Findings From the Men's Lifestyle Validation Study.American journal of epidemiology · 2022Article
- Risk factors relate to the variability of health outcomes as well as the mean: A GAMLSS tutorial.eLife · 2022Article
- Physical activity and fat-free mass during growth and in later life.The American journal of clinical nutrition · 2021Article
- A Structured Approach to Evaluating Life-Course Hypotheses: Moving Beyond Analyses of Exposed Versus Unexposed in the -Omics Context.American journal of epidemiology · 2021Article
- Article
- The Relationships between Total Protein Intake, Protein Sources, Physical Activity, and Lean Mass in a Representative Sample of the US Adults.Nutrients · 2020Article
- Physical Activity Throughout Adolescence and Peak Hip Strength in Young Adults.JAMA network open · 2020Article
- Asymmetry of Musculature and Hand Grip Strength in Bodybuilders and Martial Artists.International journal of environmental research and public health · 2020Article
- Determinants of the population health distribution: an illustration examining body mass index.International journal of epidemiology · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Fat and lean body mass have important implications for health and physical functioning in older age, and physical activity is purported to be an important modifiable determinant. However, our evidence-based understanding of its role is limited. We examined the associations of physical activity, assessed both by self-report (using data on leisure time physical activity (LTPA) collected on 4 occasions over a 28-year period) and objectively (using 5-day heart rate and movement monitoring), with fat and lean mass at ages 60-64 years in 1,162 British participants from the Medical Research Council National Survey of Health and Development in 1946-2010. Higher objectively assessed physical activity energy expenditure (PAEE) at ages 60-64 years was associated with lower fat mass and android (abdominal):gynoid (hip) fat ratio (mean differences in fat mass per 1-standard deviation increase in PAEE were -0.79 kg/m(1.2) in men (95% confidence interval: -1.08, -0.50) and -1.79 kg/m(1.2) (95% confidence interval: -2.15, -1.42) in women). After adjustment for fat mass, higher PAEE was associated with higher appendicular lean mass. Both light and moderate-to-vigorous intensities of activity were associated with fat mass, and the latter was associated with lean mass. More frequent LTPA across adulthood was associated with lower fat mass (in women only) and higher appendicular lean mass (in both sexes, after adjustment for fat mass). These results support the promotion of LTPA across adulthood, as well as both light and moderate-to-vigorous intensities of activity among older adults.
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