Evidence map›Paper›PMID 24722688›Full record

ArticleClinical rheumatology2014

Rituximab for refractory digital infarcts and ulcers in systemic sclerosis.

Chiew-Gek Khor, Xena Lung-Fang Chen, Ting-Syuan Lin, Cheng-Hsun Lu, Song-Chou Hsieh

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Old and new therapeutic strategies in systemic sclerosis (Review).Experimental and therapeutic medicine · 2022
    Review
  4. Review
  5. Review
  6. Review
  7. Vasculopathy in scleroderma.Seminars in immunopathology · 2015
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chiew-Gek KhorRheumatology Unit, Department of Internal Medicine, Pulau Pinang General Hospital, Georgetown, Malaysia.
Xena Lung-Fang Chen
Ting-Syuan Lin
Cheng-Hsun Lu
Song-Chou Hsieh
National Taiwan University Hospital · TWHospital Pulau Pinang · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic sclerosis is an uncommon connective tissue disease characterised by excessive deposition of collagen and vasculopathy which affects the skin and multiple internal organs. It is associated with autoimmunity, inflammation, vasculopathy and fibrosis. Managing Raynaud's phenonemon, digital infarcts and ulcers in systemic sclerosis patients is often a challenge particularly among rheumatologists. We report a case of systemic sclerosis patient with refractory digital infarcts and ulcers responded successfully with rituximab.

Indexed as

AdultAntibodies, Monoclonal, Murine-DerivedAutoimmunityBlood SedimentationC-Reactive ProteinFingersHumansInflammationMaleRituximabScleroderma, SystemicSkinSkin UlcerTreatment OutcomeAntibodies, Monoclonal, Murine-DerivedC-Reactive ProteinRituximab

Identifiers

PMID24722688
OpenAlexW1993288594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.