Evidence map›Paper›PMID 24722680›Full record

ArticleThe Journal of general virology2014

Molecular characterization of avian influenza H5N1 virus in Egypt and the emergence of a novel endemic subclade.

Rabeh El-Shesheny, Ahmed Kandeil, Ola Bagato, Asmaa M Maatouq, Yassmin Moatasim, Adam Rubrum, Min-Suk Song, Richard J Webby, Mohamed Ahmed Ali, Ghazi Kayali

Open access · hybridAbstract read
In one paragraph

Article in The Journal of general virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. H5 Influenza Viruses in Egypt.Cold Spring Harbor perspectives in medicine · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Rabeh El-SheshenyNational Research Centre, Giza, Egypt.
Ahmed KandeilNational Research Centre, Giza, Egypt.
Ola BagatoNational Research Centre, Giza, Egypt.
Asmaa M MaatouqNational Research Centre, Giza, Egypt.
Yassmin MoatasimNational Research Centre, Giza, Egypt.
Adam RubrumSt Jude Children's Research Hospital, Memphis, TN 38105, USA.
Min-Suk SongSt Jude Children's Research Hospital, Memphis, TN 38105, USA.
Richard J WebbySt Jude Children's Research Hospital, Memphis, TN 38105, USA.
Mohamed Ahmed AliNational Research Centre, Giza, Egypt.
Ghazi KayaliSt Jude Children's Research Hospital, Memphis, TN 38105, USA.
National Research Centre · EGSt. Jude Children's Research Hospital · US

Funding

NIAID NIH HHS HHSN266200700005C
6 · The paper itself

Abstract

Clade 2.2 highly pathogenic H5N1 viruses have been in continuous circulation in Egyptian poultry since 2006. Their persistence caused significant genetic drift that led to the reclassification of these viruses into subclades 2.2.1 and 2.2.1.1. Here, we conducted full-genome sequence and phylogenetic analyses of 45 H5N1 isolated during 2006-2013 through systematic surveillance in Egypt, and 53 viruses that were sequenced previously and available in the public domain. Results indicated that H5N1 viruses in Egypt continue to evolve and a new distinct cluster has emerged. Mutations affecting viral virulence, pathogenicity, transmission, receptor-binding preference and drug resistance were studied. In light of our findings that H5N1 in Egypt continues to evolve, surveillance and molecular studies need to be sustained.

Indexed as

PoultryAnimalsCluster AnalysisEgyptGenotypeInfluenza A Virus, H5N1 SubtypeInfluenza in BirdsMolecular Sequence DataPhylogenyRNA, ViralSequence Analysis, DNARNA, Viral

Identifiers

PMID24722680
PMCPMC4059266
OpenAlexW2010648327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.