ArticlePloS one2014
Assumed white blood cell count of 8,000 cells/μL overestimates malaria parasite density in the Brazilian Amazon.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
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- Malaria Detection Accelerated: Combing a High-Throughput NanoZoomer Platform with a ParasiteMacro Algorithm.Pathogens (Basel, Switzerland) · 2022Article
- Prevalence and risk factors of malaria among first antenatal care attendees in rural Burkina Faso.Tropical medicine and health · 2022Article
- Immunological, haematological, and clinical attributes of rural and urban malaria: a case-control study in Ghana.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- Haematological profile of children with malaria in Sorong, West Papua, Indonesia.Malaria journal · 2021Article
- Article
- Cord Malaria Infection, Complement Activation, Oxidative Stress, Gestational Age, and Birth Weight, Characterized by HighJournal of tropical medicine · 2020Article
- Malaria Parasite Density as a Predictor of Hematological Parameter Changes among HIV Infected Adults Attending Two Antiretroviral Treatment Clinics in Kano, Northwest Nigeria.Journal of tropical medicine · 2020Article
- Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana.BMC research notes · 2018Article
- Hematological Indices in Malian Children Change Significantly During a Malaria Season and with Increasing Age: Implications for Malaria Epidemiological Studies.The American journal of tropical medicine and hygiene · 2016Article
- A more appropriate white blood cell count for estimating malaria parasite density in Plasmodium vivax patients in northeastern Myanmar.Acta tropica · 2016Article
- Surmised total leucocyte counts miscalculate the parasite index of Plasmodium vivax malaria patients of tertiary and primary care settings in South-Western India.Malaria journal · 2015Article
- Comparison of three methods for detection of gametocytes in Melanesian children treated for uncomplicated malaria.Malaria journal · 2014Article
- New laboratory perspectives for evaluation of vivax malaria infected patients: a useful tool for infection monitoring.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
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8 authors.
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Abstract
Quantification of parasite density is an important component in the diagnosis of malaria infection. The accuracy of this estimation varies according to the method used. The aim of this study was to assess the agreement between the parasite density values obtained with the assumed value of 8,000 cells/μL and the automated WBC count. Moreover, the same comparative analysis was carried out for other assumed values of WBCs. The study was carried out in Brazil with 403 malaria patients who were infected in different endemic areas of the Brazilian Amazon. The use of a fixed WBC count of 8,000 cells/μL to quantify parasite density in malaria patients led to overestimated parasitemia and resulted in low reliability when compared to the automated WBC count. Assumed values ranging between 5,000 and 6,000 cells/μL, and 5,500 cells/μL in particular, showed higher reliability and more similar values of parasite density when compared between the 2 methods. The findings show that assumed WBC count of 5,500 cells/μL could lead to a more accurate estimation of parasite density for malaria patients in this endemic region.
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