Evidence map›Paper›PMID 24721801›Full record

SynthesisJournal of the American Heart Association2014

Improving blood pressure control through pharmacist interventions: a meta-analysis of randomized controlled trials.

Valérie Santschi, Arnaud Chiolero, April L Colosimo, Robert W Platt, Patrick Taffé, Michel Burnier, Bernard Burnand, Gilles Paradis

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of the American Heart Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02919033 (A Coordinated PCP-Cardiologist Telemedicine Model), which is not on this map. Cited by 173 papers, 21 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed, 21 pooled it
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02919033 naunknown statusnot on this mapstarted 2016, after this paper: background citation

A Coordinated PCP-Cardiologist Telemedicine Model (PCTM) in China's Community Hypertension Care: Study Protocol for a Randomized Controlled Trial

TypeinterventionalSponsorXu LeiRan2016 to 2018Enrolled330ConditionsHypertensionArmsUsual care, Self-management, PCTM intervention
3 · Its place in the literature

Who cites it

173 citing papers in PubMed, 21 syntheses or guidelines pooled it, 337 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Guideline
  14. Guideline
  15. Impact of integrating pharmacists into primary care teams on health systems indicators: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019
    Pooled it
  16. Guideline
  17. Pooled it
  18. Pooled it
  19. Pooled it
  20. Pooled it

113 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Valérie SantschiInstitute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.
Arnaud Chiolero
April L Colosimo
Robert W Platt
Patrick Taffé
Michel Burnier
Bernard Burnand
Gilles Paradis
Institute of Social and Preventive Medicine · CHMcGill University · CAUniversity of Lausanne · CH

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundControl of blood pressure (BP) remains a major challenge in primary care. Innovative interventions to improve BP control are therefore needed. By updating and combining data from 2 previous systematic reviews, we assess the effect of pharmacist interventions on BP and identify potential determinants of heterogeneity. METHODS AND

resultsRandomized controlled trials (RCTs) assessing the effect of pharmacist interventions on BP among outpatients with or without diabetes were identified from MEDLINE, EMBASE, CINAHL, and CENTRAL databases. Weighted mean differences in BP were estimated using random effect models. Prediction intervals (PI) were computed to better express uncertainties in the effect estimates. Thirty-nine RCTs were included with 14 224 patients. Pharmacist interventions mainly included patient education, feedback to physician, and medication management. Compared with usual care, pharmacist interventions showed greater reduction in systolic BP (-7.6 mm Hg, 95% CI: -9.0 to -6.3; I(2)=67%) and diastolic BP (-3.9 mm Hg, 95% CI: -5.1 to -2.8; I(2)=83%). The 95% PI ranged from -13.9 to -1.4 mm Hg for systolic BP and from -9.9 to +2.0 mm Hg for diastolic BP. The effect tended to be larger if the intervention was led by the pharmacist and was done at least monthly.

conclusionsPharmacist interventions - alone or in collaboration with other healthcare professionals - improved BP management. Nevertheless, pharmacist interventions had differential effects on BP, from very large to modest or no effect; and determinants of heterogeneity could not be identified. Determining the most efficient, cost-effective, and least time-consuming intervention should be addressed with further research.

Indexed as

Community Pharmacy ServicesPharmacistsProfessional RoleAntihypertensive AgentsBlood PressureCooperative BehaviorHealth Knowledge, Attitudes, PracticeHumansHypertensionInterdisciplinary CommunicationMedication Therapy ManagementPatient Care TeamPatient Education as TopicRandomized Controlled Trials as TopicTreatment OutcomeAntihypertensive Agentshypertensionpharmacistprediction intervalsystematic reviewteam‐based care

Identifiers

PMID24721801
PMCPMC4187511
OpenAlexW2133580565

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.