Evidence map›Paper›PMID 24721566›Full record

ArticleCell host & microbe2014

A host MicroRNA brokers truce with HSV-1.

Justin M Pare, Christopher S Sullivan

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell host & microbe, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. miR-138 expression in oral herpes simplex and its effect on ICP0.Experimental and therapeutic medicine · 2019
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Justin M PareThe University of Texas at Austin, Molecular Biosciences, 1 University Station A5000, Austin TX 78712-0162, USA.
Christopher S SullivanThe University of Texas at Austin, Molecular Biosciences, 1 University Station A5000, Austin TX 78712-0162, USA. Electronic address: chris_sullivan@austin.utexas.edu.

Funding

Role of microRNAs in the SV40 infectious cycleR01AI077746 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI SULLIVAN, CHRISTOPHER S. · 2009 to 2012
$1.1M
NIAID NIH HHS R01 AI077746NIAID NIH HHS R01AI077746
6 · The paper itself

Abstract

Establishing lifelong infection and periodically shedding infectious progeny is a successful strategy employed by several persistent pathogens. In this issue of Cell Host & Microbe, Pan et al. (2014) demonstrate that a cell-type-specific host microRNA can restrict gene expression and pathogenicity of herpes simplex virus 1, thereby promoting long-term infection.

Indexed as

AnimalsHerpesvirus 1, HumanHumansImmediate-Early ProteinsMaleMicroRNAsTrigeminal GanglionUbiquitin-Protein LigasesImmediate-Early ProteinsMicroRNAsMIRN138 microRNA, humanUbiquitin-Protein LigasesVmw110 protein, Human herpesvirus 1

Identifiers

PMID24721566
PMCPMC4059544

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.