Evidence map›Paper›PMID 24721130›Full record

ArticleEnvironmental research2014

Inverse association between toenail arsenic and body mass index in a population of welders.

Rachel Grashow, Jinming Zhang, Shona C Fang, Marc G Weisskopf, David C Christiani, Molly L Kile, Jennifer M Cavallari

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Arsenic and Obesity: a Review of Causation and Interaction.Current environmental health reports · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. The role of arsenic in obesity and diabetes.Journal of cellular physiology · 2019
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rachel GrashowDepartment of Environmental Health, Harvard School of Public Health, Landmark Center, 401 Park Drive, 3rd Floor, Boston, MA 02215, USA. Electronic address: rgrashow@hsph.harvard.edu.
Jinming ZhangDepartment of Environmental Health, Harvard School of Public Health, Landmark Center, 401 Park Drive, 3rd Floor, Boston, MA 02215, USA.
Shona C FangDepartment of Environmental Health, Harvard School of Public Health, Landmark Center, 401 Park Drive, 3rd Floor, Boston, MA 02215, USA; New England Research Institutes, Watertown, MA, USA.
Marc G WeisskopfDepartment of Environmental Health, Harvard School of Public Health, Landmark Center, 401 Park Drive, 3rd Floor, Boston, MA 02215, USA; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
David C ChristianiDepartment of Environmental Health, Harvard School of Public Health, Landmark Center, 401 Park Drive, 3rd Floor, Boston, MA 02215, USA; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
Molly L KileDepartment of Public Health, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA.
Jennifer M CavallariDepartment of Environmental Health, Harvard School of Public Health, Landmark Center, 401 Park Drive, 3rd Floor, Boston, MA 02215, USA; Division of Occupational and Environmental Medicine, University of Connecticut Health Center, Farmington, CT, USA.
Harvard University · USNew England Research Institutes · USOregon State University · USUConn Health · US

Funding

NATL CTR FOR CONSTRUCTION SAFETY & HEALTH RESEARCHU60OH009762 · OH · CENTER FOR CONSTRUCTION RES AND TRAINING · PI CAIN, CHRISTINA TRAHAN · 2009 to 2023
$84.6M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Marc G Weisskopf · 1985 to 2026
$44.6M
Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
The Cardiopulmonary Effects of Particulate ExposureR01ES009860 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI CHRISTIANI, DAVID C · 1999 to 2014
$4.0M
Epigenetic Effects of Prenatal Arsenic Exposure and Fetal GrowthK01ES017800 · NIEHS · OREGON STATE UNIVERSITY · PI KILE, MOLLY L · 2010 to 2014
$529k
ACL HHS U60OH009762NIEHS NIH HHS ES00002NIEHS NIH HHS ES009860NIEHS NIH HHS K01 ES017800NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES009860NIEHS NIH HHS T32 ES007069NIEHS NIH HHS T32ES7069NIOSH CDC HHS OH009762NIOSH CDC HHS U60 OH009762
6 · The paper itself

Abstract

Recent data show that arsenic may play a role in obesity-related diseases. However, urinary arsenic studies report an inverse association between arsenic level and body mass index (BMI). We explored whether toenail arsenic, a long-term exposure measure, was associated with BMI in 74 welders with known arsenic exposure. BMI showed significant inverse associations with toenail arsenic (p=0.01), which persisted in models adjusted for demographics, diet and work history. It is unclear whether low arsenic biomarker concentrations in high BMI subjects truly reflect lower exposures, or instead reflect internal or metabolic changes that alter arsenic metabolism and tissue deposition.

Indexed as

Body Mass IndexWeldingAdultArsenicHumansMaleNailsOccupational ExposureArsenicArsenicBMIMetalsOccupational healthToenailWelding fume

Identifiers

PMID24721130
PMCPMC4035809
OpenAlexW2152511639

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.