ArticleVirchows Archiv. A, Pathological anatomy and histopathology1989
Coexpression of cytokeratin, neurofilament and vimentin in carcinoid tumors.
Article in Virchows Archiv. A, Pathological anatomy and histopathology, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 16 citations in OpenAlex.
- Functioning and nonfunctioning adrenal medullary tumors.Endocrine pathology · 1991Review
- Co-expression of cytokeratin and vimentin filaments in rete testis and epididymis. An immunohistochemical study.Virchows Archiv. A, Pathological anatomy and histopathology · 1991Article
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Authors and funding
4 authors at 2 institutions in 1 country.
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Abstract
The immunohistochemical expression of intermediate filaments was investigated in 56 carcinoid tumors from 50 cases including 31 rectal and 25 non-rectal sites. Cytokeratin was the most frequently expressed in 55 of the tumours. Only one tumour of the stomach was negative for cytokeratin. Neurofilament (68 kd and 160 kd) was positive in 25 (44.6%) tumours with no preferential pattern of expression in particular tumours. Vimentin was positive in 18 out of the 31 rectal carcinoids (58%), and 3 of the 25 non-rectal carcinoids (12%). There was a significant difference in vimentin immunoreactivity between rectal and non-rectal carcinoids. The coexpression of cytokeratin and neurofilament was 44.6% and that of cytokeratin and vimentin was 37.5%. The coexpression of all three types of intermediate filament was 35.5% in rectal carcinoids, but 8% in non-rectal carcinoids. The present study revealed coexpression of cytokeratin, neurofilament and vimentin in carcinoids and an especially high incidence of vimentin expression in those of rectal origin.
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