ArticleBioMed research international2014
Early stage oropharyngeal carcinomas: comparing quality of life for different treatment modalities.
Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Trismus following different treatment modalities for head and neck cancer: a systematic review of subjective measures.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Pooled it
- Quality of Life in Oropharyngeal Cancer: A Retrospective Analysis of Patient Characteristics and Treatment Modalities.Annals of surgical oncology · 2025Article
- Oral health-related quality of life in oral cancer patients assessed with EORTC instruments: a scoping review.BMC oral health · 2025Article
- Frequency and Consequences of Cervical Lymph Node Overstaging in Head and Neck Carcinoma.Diagnostics (Basel, Switzerland) · 2022Article
- Functional Outcomes in Head and Neck Cancer Patients.Cancers · 2022Article
- Quality of life in Iranian patients with head-and-neck cancer.Journal of education and health promotion · 2020Article
- Treatment trends in head and neck cancer: Surveillance, Epidemiology, and End Results (SEER) Patterns of Care analysis.Cancer causes & control : CCC · 2019Article
- Health related quality of life following the treatment of oropharyngeal cancer by transoral laser.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Article
- Outcome and prognostic factors in T4a oropharyngeal carcinoma, including the role of HPV infection.BioMed research international · 2014Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare long-term quality of life outcomes after treating early stage oropharyngeal carcinoma either with surgery, surgery combined with radiotherapy, or surgery combined with chemoradiotherapy.
methodsQuestionnaire based method: 111 eligible patients agreed to fill out a quality of life questionnaire.
resultsOf the 32 scales contained in the EORTC's combined QLQ-C30 and HN35, 11 scales show significantly better results for the surgery-only treatment group when compared to either surgery combined with radiotherapy or surgery combined with any type of adjuvant therapy. These eleven scales are role function (P = 0.019/0.008), social function (P = 0.01/0.034), nausea (P = 0.017/0.025), pain (P = 0.014/0.023), financial problems (P = 0.030/0.012), speech (P = 0.02/0.015), social eating (P = 0.003/<0.001), mouth opening (P = 0.033/0.016), sticky saliva (P = 0.001/<0.001), swallowing (P < 0.001/<0.001), and dry mouth (P < 0.001/0.001).
conclusionTreatment of early stage oropharyngeal carcinoma with surgery alone has definite advantages over treatments including any form of adjuvant therapy when considering quality of life. Advantages manifest themselves especially in functional aspects of the head and neck realm; however general health aspects as well as psychosocial aspects show improvements as well. This study does not show any indication of QOL-related drawbacks of surgery-only treatment approaches.
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