ArticleIranian Red Crescent medical journal2014
Hepatoprotective herbs, avicenna viewpoint.
Article in Iranian Red Crescent medical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 42 citations in OpenAlex.
- Trial
- From Network Analysis to Functional Nutraceutical Protection: Pistacia lentiscus L. Mitigates DMBA-Induced Liver Damage Through AhR/ARNT Pathway Regulation.Chemistry & biodiversity · 2026Article
- Tiryāq in traditional Persian medicine: a survey of antidotal plants and their modern pharmacological potential.Frontiers in pharmacology · 2025Review
- A Scoping Review on Hepatoprotective Mechanism of Herbal Preparations through Gut Microbiota Modulation.Current issues in molecular biology · 2024Article
- An overview of pharmacological effects of Crocus sativous and its constituents.Iranian journal of basic medical sciences · 2024Review
- Alpinetin: A Review of Its Pharmacology and Pharmacokinetics.Frontiers in pharmacology · 2022Review
- Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Effects ofAntioxidants (Basel, Switzerland) · 2020Article
- Cautiously using natural medicine to treat liver problems.World journal of gastroenterology · 2017Article
- Exploring Hepatitis From the Perspective of Iranian Traditional Medicine: Using a Qualitative Approach.Journal of evidence-based complementary & alternative medicine · 2017Review
- Therapeutic effects of saffron (Crocus sativus L.) in digestive disorders: a review.Iranian journal of basic medical sciences · 2016Review
- Plants Consumption and Liver Health.Evidence-based complementary and alternative medicine : eCAM · 2015Review
- The liver in Greco-Arabic and Islamic medicine.Clinical liver diseaseReview
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLiver injury or dysfunction is considered as a serious health problem. The available synthetic drugs to treat liver disorders are expensive and cause further damage. Hence, hepatoprotective effects of some herbal drugs have been investigated, and one of the methods to choose herbs in order to study their biological effects is to search in ancient medical texts. Avicenna who is known as the prince of physicians had collected and classified Greek, Persian and Islamic medicine in the best possible way in the book of Canon in Arabic.
objectivesAvicenna's book of The Canon of Medicine was reviewed to find the hepatoprotective herbs. PATIENTS AND
methodsThree different versions of the Canon were prepared and utilized. To find scientific names of plants we took advantage of three botany references. All of the herbs were investigated on the basis of scientific data from hepatoprotective effects point of view. The searched term was "hepatoprotective" without narrowing and limiting. The searched databases included Cochrane library, Web of science, SID, Irandoc and IranMedex.
results18 plants were found. 85% of the presented species, genus or families of plants were reported to have hepatoprotective properties and in the remaining 15% there were no reports of hepatoprotective effect. Flowers and fruits were the most used part of the plants. Most of the plants had simultaneous protective effects on multiple organs but the protective effect on the liver was mostly accompanied by protective effect on the stomach (83%). The average temperament of these herbs is "hot" in the 2nd phase of the 2nd grade, and "dry" in the 3rd phase of the 2nd grade. Hepatoprotective herbs mostly prescribed as a part of hepatoprotective compound drugs formula or other formula for liver diseases are Crocus sativus, Pistacia lentiscus, and Cinnamomum spp.
conclusionsMaybe there is common mechanism for protecting both liver and stomach. Aquilaria agallocha, Aquilaria malaccensis, and Ruscus aculeatus whose hepatoprotective effects have not yet been reported are considered as good candidates for future investigations. Given that Crocus sativus, and Cinnamomum spp are used as flavors in most countries, they will be introduced for more investigation in order to produce hepatoprotective drugs.
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