ArticleEvidence-based complementary and alternative medicine : eCAM2014
Effects of Mentha suaveolens Essential Oil Alone or in Combination with Other Drugs in Candida albicans.
Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed, 129 citations in OpenAlex.
- Synergistic Effect of Essential Oils and Antifungal Agents in Fighting Resistant Clinical Isolates ofPharmaceutics · 2024Article
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- Carvacrol-Induced Vacuole Dysfunction and Morphological Consequences inMicroorganisms · 2023Article
- Chemical Composition and Anti-Molecules (Basel, Switzerland) · 2023Article
- Cinnamon Leaf and Clove Essential Oils Are Potent Inhibitors ofMicroorganisms · 2022Article
- Combining Essential Oils with Each Other and with Clotrimazole Prevents the Formation ofPharmaceutics · 2022Article
- Antifungal Activity of Select Essential Oils againstPathogens (Basel, Switzerland) · 2022Article
- Terpinen-4-ol, the Main Bioactive Component of Tea Tree Oil, as an Innovative Antimicrobial Agent againstPathogens (Basel, Switzerland) · 2022Article
- Article
- Antifungal Carvacrol Loaded Chitosan Nanoparticles.Antibiotics (Basel, Switzerland) · 2021Article
- Effect of Clove and Thyme Essential Oils onMolecules (Basel, Switzerland) · 2019Article
- Antioxidant, Antifungal, Antibiofilm, and Cytotoxic Activities ofMedicines (Basel, Switzerland) · 2018Review
- Reversal of Azole Resistance in Candida albicans by Sulfa Antibacterial Drugs.Antimicrobial agents and chemotherapy · 2018Article
- Antimicrobial and Antibiofilm Activity and Machine Learning Classification Analysis of Essential Oils from Different Mediterranean Plants against Pseudomonas aeruginosa.Molecules (Basel, Switzerland) · 2018Article
- The Confrontation between Ethnopharmacology and Pharmacological Tests of Medicinal Plants Associated with Mental and Neurological Disorders.Evidence-based complementary and alternative medicine : eCAM · 2018Review
- Evaluation of synergistic anticandidal and apoptotic effects of ferulic acid and caspofungin against Candida albicans.Journal of food and drug analysis · 2018Article
- Essential Oils and Antifungal Activity.Pharmaceuticals (Basel, Switzerland) · 2017Review
- Candida albicans Impairments Induced by Peppermint and Clove Oils at Sub-Inhibitory Concentrations.International journal of molecular sciences · 2017Article
- Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry.Molecules (Basel, Switzerland) · 2017Review
- A Comparative Analysis of the Chemical Composition, Anti-Inflammatory, and Antinociceptive Effects of the Essential Oils from Three Species of Mentha Cultivated in Romania.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Candidosis is the most important cause of fungal infections in humans. The yeast Candida albicans can form biofilms, and it is known that microbial biofilms play an important role in human diseases and are very difficult to treat. The prolonged treatment with drugs has often resulted in failure and resistance. Due to the emergence of multidrug resistance, alternatives to conventional antimicrobial therapy are needed. This study aims to analyse the effects induced by essential oil of Mentha suaveolens Ehrh (EOMS) on Candida albicans and its potential synergism when used in combination with conventional drugs. Morphological differences between control and EOMS treated yeast cells or biofilms were observed by scanning electron microscopy and transmission electron microscopy (SEM and TEM resp.,). In order to reveal the presence of cell cycle alterations, flow cytometry analysis was carried out as well. The synergic action of EOMS was studied with the checkerboard method, and the cellular damage induced by different treatments was analysed by TEM. The results obtained have demonstrated both the effects of EOMS on C. albicans yeast cells and biofilms and the synergism of EOMS when used in combination with conventional antifungal drugs as fluconazole (FLC) and micafungin (MCFG), and therefore we can hypothesize on its potential use in therapy. Further studies are necessary to know its mechanism of action.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.