Evidence map›Paper›PMID 24719499›Full record

ArticleDisease markers2014

Avocado oil supplementation modifies cardiovascular risk profile markers in a rat model of sucrose-induced metabolic changes.

Octavio Carvajal-Zarrabal, Cirilo Nolasco-Hipolito, M Guadalupe Aguilar-Uscanga, Guadalupe Melo-Santiesteban, Patricia M Hayward-Jones, Dulce M Barradas-Dermitz

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 59 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. The Pulp, Peel, Seed, and Food Products ofInternational journal of molecular sciences · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. The Odyssey of Bioactive Compounds in Avocado (Antioxidants (Basel, Switzerland) · 2019
    Review
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Octavio Carvajal-ZarrabalBiochemical and Nutrition Chemistry Area, University of Veracruz, SS Juan Pablo II s/n, 94294 Boca del Río, Ver., Mexico.
Cirilo Nolasco-HipolitoDepartment of Molecular Biology, Faculty of Resource Science and Technology, University Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia.
M Guadalupe Aguilar-UscangaFood Research and Development Unit, Veracruz Institute of Technology, Calz. M.A. de Quevedo 2779, 91860 Veracruz, Ver., Mexico.
Guadalupe Melo-SantiestebanPathology Laboratory, Institute of Forensic Medicine, University of Veracruz, SS Juan Pablo II s/n, 94294 Boca del Río, Ver., Mexico.
Patricia M Hayward-JonesBiochemical and Nutrition Chemistry Area, University of Veracruz, SS Juan Pablo II s/n, 94294 Boca del Río, Ver., Mexico.
Dulce M Barradas-DermitzBiological-Chemistry Area, Veracruz Institute of Technology, Calz. M.A. de Quevedo 2779, 91860 Veracruz, Ver., Mexico.
Universidad Veracruzana · MXInstituto Tecnologico de Veracruz · MXUniversiti Malaysia Sarawak · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to evaluate the effects of avocado oil administration on biochemical markers of cardiovascular risk profile in rats with metabolic changes induced by sucrose ingestion. Twenty-five rats were divided into five groups: a control group (CG; basic diet), a sick group (MC; basic diet plus 30% sucrose solution), and three other groups (MCao, MCac, and MCas; basic diet plus 30% sucrose solution plus olive oil and avocado oil extracted by centrifugation or using solvent, resp.). Glucose, total cholesterol, triglycerides, phospholipids, low- and high-density lipoproteins (LDL, HDL), very low-density lipoprotein (VLDL), lactic dehydrogenase, creatine kinase, and high sensitivity C-reactive protein concentration were analyzed. Avocado oil reduces TG, VLDL, and LDL levels, in the LDL case significantly so, without affecting HDL levels. An effect was exhibited by avocado oil similar to olive oil, with no significant difference between avocado oil extracted either by centrifugation or solvent in myocardial injury biochemical indicators. Avocado oil decreased hs-CRP levels, indicating that inflammatory processes were partially reversed. These findings suggested that avocado oil supplementation has a positive health outcome because it reduces inflammatory events and produces positive changes in the biochemical indicators studied, related to the development of metabolic syndrome.

Indexed as

AnimalsBiomarkersCardiovascular AgentsCardiovascular DiseasesC-Reactive ProteinDietary SupplementsDisease Models, AnimalDrug Evaluation, PreclinicalFruitHumansLipoproteins, HDLLipoproteins, LDLMalePerseaPlant OilsRats, Sprague-DawleyBiomarkersCardiovascular AgentsC-Reactive ProteinLipoproteins, HDLLipoproteins, LDLPlant Oils

Identifiers

PMID24719499
PMCPMC3955619
OpenAlexW2044466845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.