Evidence map›Paper›PMID 24719438›Full record

ArticleJournal of clinical microbiology2014

Detection of prosthetic joint infection by use of PCR-electrospray ionization mass spectrometry applied to synovial fluid.

Dante P Melendez, James R Uhl, Kerryl E Greenwood-Quaintance, Arlen D Hanssen, Rangarajan Sampath, Robin Patel

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. A Real Pain: Diagnostic Quandaries and Septic Arthritis.Journal of clinical microbiology · 2018
    Review
  8. Review
  9. Article
  10. Molecular diagnostics.The Journal of the American Academy of Orthopaedic Surgeons · 2015
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dante P MelendezDivision of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
James R UhlDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Kerryl E Greenwood-QuaintanceDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Arlen D HanssenDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Rangarajan SampathIbis Biosciences, Abbott Company, Carlsbad, California, USA.
Robin PatelDivision of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA patel.robin@mayo.edu.
Mayo Clinic · USMayo Clinic in Florida · USAbbott (United States) · US

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
The Electricidal Effect, a Novel Anti-Biofilm StrategyR01AI091594 · NIAID · MAYO CLINIC ROCHESTER · PI Haluk Beyenal, Robin Patel · 2011 to 2026
$5.5M
Molecular Detection of Biofilms on Hip and Knee ImplantsR01AR056647 · NIAMS · MAYO CLINIC ROCHESTER · PI PATEL, ROBIN · 2009 to 2020
$4.5M
NCATS NIH HHS UL1 TR000135NIAID NIH HHS R01 AI091594NIAID NIH HHS R01 AI91594NIAMS NIH HHS R01 AR056647
6 · The paper itself

Abstract

PCR coupled with electrospray ionization mass spectrometry applied to synovial fluid specimens had an 81% sensitivity and a 95% specificity for the diagnosis of prosthetic joint infection.

Indexed as

AgedAged, 80 and overArthritisFemaleHumansMaleMiddle AgedPolymerase Chain ReactionProsthesis-Related InfectionsSensitivity and SpecificitySpectrometry, Mass, Electrospray IonizationSynovial Fluid

Identifiers

PMID24719438
PMCPMC4042771
OpenAlexW1999530047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.