ReviewExperimental biology and medicine (Maywood, N.J.)2014
Obesity and asthma: pathophysiology and implications for diagnosis and management in primary care.
Review in Experimental biology and medicine (Maywood, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Role of Leptin as a Link between Asthma and Obesity: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2022Pooled it
- Examining adolescents' obesogenic behaviors on structured days: a systematic review and meta-analysis.International journal of obesity (2005) · 2022Pooled it
- State-of-the-art of measures of the obesogenic environment for children.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Pooled it
- Developing a core outcome set for childhood obesity prevention: A systematic review.Maternal & child nutrition · 2019Pooled it
- Country-specific differences in the association between obesity risk factors in two high-income countries: a cross-sectional analysis from the Prospective Urban Rural Epidemiology (PURE) study.BMC public health · 2026Article
- Obesity and respiratory diseases: mechanisms, phenotypes, and clinical implications.Diabetology & metabolic syndrome · 2026Review
- An Observational Study of the Role of Adiponectin and Vitamin D in Pediatric Asthma and Obesity.Children (Basel, Switzerland) · 2026Article
- Association between lipid accumulation product and asthma in US adults: evidence from the NHANES 2005-2020.BMC pulmonary medicine · 2026Article
- The Impact of Obesity on Airway Inflammation, Lung Function and Biologic Treatment in Asthma: A Narrative Review.Journal of inflammation research · 2026Review
- Predictors of poor control in adults with bronchial asthma.Bioinformation · 2026Article
- The Real-World Impact of Glucagon-Like Peptide 1 Receptor Agonists on Asthma Control in People with High-Risk Asthma and Obesity.Advances in therapy · 2025Article
- Pregnancy does not affect progression of mild experimental asthma in sheep.The Journal of physiology · 2025Article
- The causal association between asthma and the risk of frailty: A two-sample Mendelian randomization study.Aging clinical and experimental research · 2024Article
- Effectiveness of a nutrition education intervention using simulation videos and encouragement of parental involvement for elementary school students.Journal of nutritional science · 2024Article
- Beyond the Metabolic Syndrome: Non-Obvious Complications of Obesity in Children.Children (Basel, Switzerland) · 2023Review
- A Review of the Effects of Adolescent Cannabis Use on Physical Health.The Psychiatric clinics of North America · 2023Review
- Breastfeeding is associated with reduced risks of central obesity and hypertension in young school-aged children: a large, population-based study.International breastfeeding journal · 2023Article
- Longitudinal weight status and academic achievement in elementary schoolchildren in the United States.International journal of obesity (2005) · 2023Article
- Platelet Serotonin (5-HT) Concentration, Platelet Monoamine Oxidase B (MAO-B) Activity andBiomolecules · 2023Article
- PPARδ Agonist GW501516 Suppresses the TGF-β-Induced Profibrotic Response of Human Bronchial Fibroblasts from Asthmatic Patients.International journal of molecular sciences · 2023Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The effects of obesity on asthma diagnosis, control, and exacerbation severity are increasingly recognized; however, the underlying pathophysiology of this association is poorly understood. Mainstream clinical practice has yet to adopt aggressive management of obesity as a modifiable risk factor in asthma care, as is the case with a risk factor like tobacco or allergen exposure. This review summarizes existing data that support the pathophysiologic mechanisms underlying the association between obesity and asthma, as well as the current and future state of treatment for the obese patient with asthma. Our review suggests that evidence of chronic inflammatory response linking obesity and asthma indicates a need to address obesity during asthma management, possibly using patient-centered approaches such as shared decision making. There is a need for research to better understand the mechanisms of asthma in the obese patient and to develop new therapies specifically targeted to this unique patient population.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.