ArticleJournal of magnetic resonance imaging : JMRI2014
Liver stiffness assessment with tagged MRI of cardiac-induced liver motion in cirrhosis patients.
Article in Journal of magnetic resonance imaging : JMRI, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Harnessing intrinsic cardiac motion vs. external mechanical vibrations: a comparison of MRI cine-tagging and MR elastography for liver fibrosis assessment.The British journal of radiology · 2025Article
- Retrospective review of patient factors impacting free-breathing respiratory motion magnitude for MR-guided radiotherapy.Technical innovations & patient support in radiation oncology · 2025Article
- Motion-compensation approach for quantitative digital subtraction angiography and its effect onJournal of medical imaging (Bellingham, Wash.) · 2024Article
- Native-resolution myocardial principal Eulerian strain mapping using convolutional neural networks and Tagged Magnetic Resonance Imaging.Computers in biology and medicine · 2022Article
- Cardiac-induced liver deformation as a measure of liver stiffness using dynamic imaging without magnetization tagging-preclinical proof-of-concept, clinical translation, reproducibility and feasibility in patients with cirrhosis.Abdominal radiology (New York) · 2021Article
- Retrospective four-dimensional magnetic resonance imaging of liver: Method development.Journal of applied clinical medical physics · 2020Article
- Usefulness of Virtual Expiratory CT Images to Compensate for Respiratory Liver Motion in Ultrasound/CT Image Fusion: A Prospective Study in Patients with Focal Hepatic Lesions.Korean journal of radiology · 2019Article
- Respiration-Induced Intraorgan Deformation of the Liver: Implications for Treatment Planning in Patients Treated With Fiducial Tracking.Technology in cancer research & treatment · 2017Article
- Magnetization-tagged MRI is a simple method for predicting liver fibrosis.Clinical and molecular hepatology · 2016Article
- Liver lobe-based magnetic resonance diffusion-weighted imaging using multiple b values in patients with hepatitis B-related liver cirrhosis: association with the liver disease severity according to the Child-Pugh class.Clinics (Sao Paulo, Brazil) · 2015Article
- Motion correction options in PET/MRI.Seminars in nuclear medicine · 2015Review
- Optimization of tagged MRI for quantification of liver stiffness using computer simulated data.PloS one · 2014Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeTo assess liver stiffness using magnetization-tagged magnetic resonance imaging (MRI) to measure the cardiac-induced motion in the liver of cirrhosis patients with known Child-Pugh scores. MATERIALS AND
methodsTagged MRI was performed using a 3T MR scanner on 52 cirrhosis patients classified into two groups: liver cirrhosis with Child-Pugh A (LCA; n = 39) and liver cirrhosis with Child-Pugh B or C (LCBC; n = 13). We also included 19 healthy controls. Tagged images were acquired encompassing both the liver and the heart. The corresponding displacement and strains were calculated using a Gabor filter bank. The maximum displacement (MaxDisp) was found over the cardiac cycle, as well as the local maximum P1 (MaxP1) and minimum P2 strains (MinP2). Group comparisons were made without and with adjustment for age and gender.
resultsIn control, LCA, and LCBC groups, the MaxDisp was 3.98 ± 0.88 mm, 2.52 ± 0.73 mm, and 1.86 ± 0.77 mm; the MaxP1 was 0.10 ± 0.02, 0.04 ± 0.01, and 0.02 ± 0.01; and the MinP2 was -0.08 ± 0.01, -0.05 ± 0.02, and -0.03 ± 0.01, respectively. Statistically significant differences were found between groups (P < 0.05 for all).
conclusionThis method measures cardiac-induced liver motion and deformation to assess liver stiffness. Significant differences were found in our stiffness measures between control, LCA, and LCBC groups, with more severe disease being associated with greater stiffness.
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