ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Microcircuitry of agranular frontal cortex: testing the generality of the canonical cortical microcircuit.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed.
- Intrinsic neuronal diversity as a substrate for cortical area specialization in primate vision.Nature communications · 2026Article
- Laminar architecture of visual and auditory responses in the supplementary eye field of macaques.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Noninvasive profiling of input-output excitability curves in human prefrontal cortex.bioRxiv : the preprint server for biology · 2025Article
- A ubiquitous spectrolaminar motif across independent studies, including Mackey et al.'s own data.bioRxiv : the preprint server for biology · 2025Article
- Multimodal gradients unify local and global cortical organization.Nature communications · 2025Article
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- The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow.Nature neuroscience · 2025Article
- A preparatory cranial potential for saccadic eye movements in macaque monkeys.bioRxiv : the preprint server for biology · 2025Article
- Propofol-mediated loss of consciousness disrupts predictive routing and local field phase modulation of neural activity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Laminar Dynamics of Target Selection in the Posterior Parietal Cortex of the Common Marmoset.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- A ubiquitous spectrolaminar motif of local field potential power across the primate cortex.Nature neuroscience · 2024Article
- Agranular frontal cortical microcircuit underlying cognitive control in macaques.Frontiers in neural circuits · 2024Review
- Cortical origin of theta error signals.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Acquisition and processing methods of whole-brain layer-fMRI VASO and BOLD: The Kenshu dataset.Aperture neuro · 2023Article
- Rapid Input-Output Transformation between Local Field Potential and Spiking Activity during Sensation but not Action in the Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
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- A physical neural mass model framework for the analysis of oscillatory generators from laminar electrophysiological recordings.NeuroImage · 2023Article
- Neurophysiological mechanisms of error monitoring in human and non-human primates.Nature reviews. Neuroscience · 2023Review
- Age-related changes in the primary auditory cortex of newborn, adults and aging bottlenose dolphins (Frontiers in neuroanatomy · 2023Article
- Resolving the mesoscopic missing link: Biophysical modeling of EEG from cortical columns in primates.NeuroImage · 2022Article
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4 authors.
Funding
Abstract
We investigated whether a frontal area that lacks granular layer IV, supplementary eye field, exhibits features of laminar circuitry similar to those observed in primary sensory areas. We report, for the first time, visually evoked local field potentials (LFPs) and spiking activity recorded simultaneously across all layers of agranular frontal cortex using linear electrode arrays. We calculated current source density from the LFPs and compared the laminar organization of evolving sinks to those reported in sensory areas. Simultaneous, transient synaptic current sinks appeared first in layers III and V followed by more prolonged current sinks in layers I/II and VI. We also found no variation of single- or multi-unit visual response latency across layers, and putative pyramidal neurons and interneurons displayed similar response latencies. Many units exhibited pronounced discharge suppression that was strongest in superficial relative to deep layers. Maximum discharge suppression also occurred later in superficial than in deep layers. These results are discussed in the context of the canonical cortical microcircuit model originally formulated to describe early sensory cortex. The data indicate that agranular cortex resembles sensory areas in certain respects, but the cortical microcircuit is modified in nontrivial ways.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.