ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Slow-wave sleep-imposed replay modulates both strength and precision of memory.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.
- Promoting memory consolidation during sleep: A meta-analysis of targeted memory reactivation.Psychological bulletin · 2020Pooled it
- Second-order threat conditioning in the amygdala-posterior piriform cortex network.Communications biology · 2025Article
- Article
- Selective Modulation of Fear Memory in Non-Rapid Eye Movement Sleep.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Threat Memory in the Sensory Cortex: Insights from Olfaction.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024Review
- Neural correlates of sleep-induced benefits on traumatic memory processing.Human brain mapping · 2023Article
- Multi-channel recordings reveal age-related differences in the sleep of juvenile and adult zebra finches.Scientific reports · 2023Article
- Sleep prevents catastrophic forgetting in spiking neural networks by forming a joint synaptic weight representation.PLoS computational biology · 2022Article
- Sleep facilitates spatial memory but not navigation using the Minecraft Memory and Navigation task.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- State-dependent olfactory processing in freely behaving mice.Cell reports · 2022Article
- A model of bi-directional interactions between complementary learning systems for memory consolidation of sequential experiences.Frontiers in systems neuroscience · 2022Article
- Reciprocal relationships between sleep and smell.Frontiers in neural circuits · 2022Review
- Targeted Memory Reactivation During REM Sleep in Patients With Social Anxiety Disorder.Frontiers in psychiatry · 2022Article
- Exposure to Olfactory Alcohol Cues During Non-rapid Eye Movement Sleep Did Not Decrease Craving in Patients With Alcohol Dependence.Frontiers in psychiatry · 2022Article
- Molecular Mechanisms of Memory Consolidation That Operate During Sleep.Frontiers in molecular neuroscience · 2021Review
- Experience and sleep-dependent synaptic plasticity: from structure to activity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Stimulation Augments Spike Sequence Replay and Memory Consolidation during Slow-Wave Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Neurochemical mechanisms for memory processing during sleep: basic findings in humans and neuropsychiatric implications.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Review
- Sharp-wave ripples as a signature of hippocampal-prefrontal reactivation for memory during sleep and waking states.Neurobiology of learning and memory · 2019Review
- Sleep disturbances are common in patients with autoimmune encephalitis.Journal of neurology · 2019Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Odor perception is hypothesized to be an experience-dependent process involving the encoding of odor objects by distributed olfactory cortical ensembles. Olfactory cortical neurons coactivated by a specific pattern of odorant evoked input become linked through association fiber synaptic plasticity, creating a template of the familiar odor. In this way, experience and memory play an important role in odor perception and discrimination. In other systems, memory consolidation occurs partially via slow-wave sleep (SWS)-dependent replay of activity patterns originally evoked during waking. SWS is ideal for replay given hyporesponsive sensory systems, and thus reduced interference. Here, using artificial patterns of olfactory bulb stimulation in a fear conditioning procedure in the rat, we tested the effects of imposed post-training replay during SWS and waking on strength and precision of pattern memory. The results show that imposed replay during post-training SWS enhanced the subsequent strength of memory, whereas the identical replay during waking induced extinction. The magnitude of this enhancement was dependent on the timing of imposed replay relative to cortical sharp-waves. Imposed SWS replay of stimuli, which differed from the conditioned stimulus, did not affect conditioned stimulus memory strength but induced generalization of the fear memory to novel artificial patterns. Finally, post-training disruption of piriform cortex intracortical association fiber synapses, hypothesized to be critical for experience-dependent odor coding, also impaired subsequent memory precision but not strength. These results suggest that SWS replay in the olfactory cortex enhances memory consolidation, and that memory precision is dependent on the fidelity of that replay.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.