ReviewEndocrine pathology2014
Hyperplasia to neoplasia sequence of duodenal and pancreatic neuroendocrine diseases and pseudohyperplasia of the PP-cells in the pancreas.
Review in Endocrine pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- [Multiple neuroendocrine tumors of the pancreas].Pathologie (Heidelberg, Germany) · 2024Review
- [Exocrine meets neuroendocrine: mimickers of pancreatic neuroendocrine neoplasms].Pathologie (Heidelberg, Germany) · 2024Review
- Case report: Insulinomatosis: description of four sporadic cases and review of the literature.Frontiers in endocrinology · 2023Review
- Complete remission of recurrent multiple insulin-producing neuroendocrine tumors of the pancreas with somatostatin analogs: a case report and literature review.Discover oncology · 2022Article
- Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice.Diabetologia · 2021Article
- Sporadic Multifocal Gastrinoma Mimicking a Duodenal GIST, in a Patient with MEN1 Gene Polymorphism D418D: an Unusual Case Report.Journal of gastrointestinal cancer · 2021Article
- Molecular Pathology of Well-Differentiated Gastro-entero-pancreatic Neuroendocrine Tumors.Endocrine pathology · 2021Review
- Pancreatic neuroendocrine neoplasms: current state and ongoing controversies on terminology, classification and prognostication.Journal of gastrointestinal oncology · 2020Review
- Not only stem cells, but also mature cells, particularly neuroendocrine cells, may develop into tumours: time for a paradigm shift.Therapeutic advances in gastroenterology · 2018Review
- Neuroendocrine Neoplasms: Dichotomy, Origin and Classifications.Visceral medicine · 2017Review
- Current knowledge on the sensitivity of the (68)Ga-somatostatin receptor positron emission tomography and the SUVmax reference range for management of pancreatic neuroendocrine tumours.European journal of nuclear medicine and molecular imaging · 2016Review
- Surgical and molecular pathology of pancreatic neoplasms.Diagnostic pathology · 2016Review
- Elusive liver factor that causes pancreatic α cell hyperplasia: A review of literature.World journal of gastrointestinal pathophysiology · 2015Review
- [What is new in the pathology of pancreatic neuroendocrine tumors?].Der Pathologe · 2015Review
- Glucagon receptor gene mutations with hyperglucagonemia but without the glucagonoma syndrome.World journal of gastrointestinal surgery · 2015Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyperplastic changes of the neuroendocrine cell system may have the potential to evolve into neoplastic diseases. This is particularly the case in the setting of genetically determined and hereditary neuroendocrine tumor syndromes such as MEN1. The review discusses the MEN1-associated hyperplasia-neoplasia sequence in the development of gastrinomas in the duodenum and glucagon-producing tumors in the pancreas. It also presents other newly described diseases (e.g., glucagon cell adenomatosis and insulinomatosis) in which the tumors are (or most likely) also preceded by islet cell hyperplasia. Finally, the pseudohyperplasia of PP-rich islets in the pancreatic head is defined as a physiologic condition clearly differing from other hyperplastic-neoplastic neuroendocrine diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.