ArticleBrain structure & function2015
Aging and response conflict solution: behavioural and functional connectivity changes.
Article in Brain structure & function, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Common and distinct neural correlates of dual-tasking and task-switching: a meta-analytic review and a neuro-cognitive processing model of human multitasking.Brain structure & function · 2019Pooled it
- Three key regions for supervisory attentional control: evidence from neuroimaging meta-analyses.Neuroscience and biobehavioral reviews · 2015Pooled it
- Affective distraction by emotional arousal during visual attention: a comparative study with young and older adults.Cognitive processing · 2026Article
- An Imaging-Guided Neural Model Explains Lexical Stress Alteration in Acquired Apraxia of Speech.Human brain mapping · 2025Article
- Predicting response speed and age from task-evoked effective connectivity.Network neuroscience (Cambridge, Mass.) · 2025Article
- Impact of data processing varieties on DCM estimates of effective connectivity from task-fMRI.Human brain mapping · 2024Article
- Predicting executive functioning from brain networks: modality specificity and age effects.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Altered age-related alpha and gamma prefrontal-occipital connectivity serving distinct cognitive interference variants.NeuroImage · 2023Article
- Brain functional characterization of response-code conflict in dual-tasking and its modulation by age.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Predicting Executive Functioning from Brain Networks: Modality Specificity and Age Effects.bioRxiv : the preprint server for biology · 2023Article
- Predicting executive functioning from functional brain connectivity: network specificity and age effects.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Movement-Related Gamma Synchrony Differentially Predicts Behavior in the Presence of Visual Interference Across the Lifespan.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Differential Effects of a Nap on Motor Sequence Learning-Related Functional Connectivity Between Young and Older Adults.Frontiers in aging neuroscience · 2021Article
- Stronger Functional Connectivity in the Default Mode and Salience Networks Is Associated With Youthful Memory in Superaging.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Insular Risk Processing Predicts Alcohol Use Via Externalizing Pathway in Male Adolescents.Journal of studies on alcohol and drugs · 2019Article
- A network view on brain regions involved in experts' object and pattern recognition: Implications for the neural mechanisms of skilled visual perception.Brain and cognition · 2019Article
- Towards a human self-regulation system: Common and distinct neural signatures of emotional and behavioural control.Neuroscience and biobehavioral reviews · 2018Review
- Dissociable Effects of Aging on Salience Subnetwork Connectivity Mediate Age-Related Changes in Executive Function and Affect.Frontiers in aging neuroscience · 2018Article
- Hemispheric Lateralization of Resting-State Functional Connectivity of the Anterior Insula: Association with Age, Gender, and a Novelty-Seeking Trait.Brain connectivity · 2016Article
- Altered resting-state network connectivity in stroke patients with and without apraxia of speech.NeuroImage. Clinical · 2015Article
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7 authors.
Funding
Abstract
Healthy aging has been found associated with less efficient response conflict solution, but the cognitive and neural mechanisms have remained elusive. In a two-experiment study, we first examined the behavioural consequences of this putative age-related decline for conflicts induced by spatial stimulus-response incompatibility. We then used resting-state functional magnetic resonance imaging data from a large, independent sample of adults (n = 399; 18-85 years) to investigate age differences in functional connectivity between the nodes of a network previously found associated with incompatibility-induced response conflicts in the very same paradigm. As expected, overcoming interference from conflicting response tendencies took longer in older adults, even after accounting for potential mediator variables (general response speed and accuracy, motor speed, visuomotor coordination ability, and cognitive flexibility). Experiment 2 revealed selective age-related decreases in functional connectivity between bilateral anterior insula, pre-supplementary motor area, and right dorsolateral prefrontal cortex. Importantly, these age effects persisted after controlling for regional grey-matter atrophy assessed by voxel-based morphometry. Meta-analytic functional profiling using the BrainMap database showed these age-sensitive nodes to be more strongly linked to highly abstract cognition, as compared with the remaining network nodes, which were more strongly linked to action-related processing. These findings indicate changes in interregional coupling with age among task-relevant network nodes that are not specifically associated with conflict resolution per se. Rather, our behavioural and neural data jointly suggest that healthy aging is associated with difficulties in properly activating non-dominant but relevant task schemata necessary to exert efficient cognitive control over action.
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