ArticlePloS one2014
Cardio-respiratory coordination increases during sleep apnea.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 50 citations in OpenAlex.
- Temporal Properties of Cardiorespiratory Coupling in Patients with Heart Failure During the Circadian Cycle.Entropy (Basel, Switzerland) · 2026Article
- Predictive Modeling of Heart Rate from Respiratory Signals at Rest in Young Healthy Humans.Entropy (Basel, Switzerland) · 2024Article
- On the cardiorespiratory coordination assessed by the photoplethysmography imaging technique.Scientific reports · 2023Article
- Validation of subjective manual palpation using objective physiological recordings of the cranial rhythmic impulse during osteopathic manipulative intervention.Scientific reports · 2023Article
- Directional couplings between the respiration and parasympathetic control of the heart rate during sleep and wakefulness in healthy subjects at different ages.Frontiers in network physiology · 2022Article
- Assessment of Cardiorespiratory Interactions during Apneic Events in Sleep via Fuzzy Kernel Measures of Information Dynamics.Entropy (Basel, Switzerland) · 2021Article
- Heart rate variability spectrum characteristics in children with sleep apnea.Pediatric research · 2021Article
- A Transfer Entropy Approach for the Assessment of the Impact of Inspiratory Muscle Training on the Cardiorespiratory Coupling of Amateur Cyclists.Frontiers in physiology · 2020Article
- Cardiac Autonomic Dysfunction and Incidence ofFrontiers in physiology · 2020Article
- Dynamical disentanglement in an analysis of oscillatory systems: an application to respiratory sinus arrhythmia.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2019Article
- Control of heart rate through guided high-rate breathing.Scientific reports · 2019Article
- Cardiorespiratory Temporal Causal Links and the Differences by Sport or Lack Thereof.Frontiers in physiology · 2019Article
- Paced Breathing Increases the Redundancy of Cardiorespiratory Control in Healthy Individuals and Chronic Heart Failure Patients.Entropy (Basel, Switzerland) · 2018Article
- Discovery of Causal Paths in Cardiorespiratory Parameters: A Time-Independent Approach in Elite Athletes.Frontiers in physiology · 2018Article
- Heart rate acceleration runs and deceleration runs in patients with obstructive sleep apnea syndrome.Sleep & breathing = Schlaf & Atmung · 2017Article
- Modulations of Heart Rate, ECG, and Cardio-Respiratory Coupling Observed in Polysomnography.Frontiers in physiology · 2016Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular diseases are the main source of morbidity and mortality in the United States with costs of more than $170 billion. Repetitive respiratory disorders during sleep are assumed to be a major cause of these diseases. Therefore, the understanding of the cardio-respiratory regulation during these events is of high public interest. One of the governing mechanisms is the mutual influence of the cardiac and respiratory oscillations on their respective onsets, the cardio-respiratory coordination (CRC). We analyze this mechanism based on nocturnal measurements of 27 males suffering from obstructive sleep apnea syndrome. Here we find, by using an advanced analysis technique, the cardiogram, not only that the occurrence of CRC is significantly more frequent during respiratory sleep disturbances than in normal respiration (p-value<10(-51)) but also more frequent after these events (p-value<10(-15)). Especially, the latter finding contradicts the common assumption that spontaneous CRC can only be observed in epochs of relaxed conditions, while our newly discovered epochs of CRC after disturbances are characterized by high autonomic stress. Our findings on the connection between CRC and the appearance of sleep-disordered events require a substantial extension of the current understanding of obstructive sleep apneas and hypopneas.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.