Trial reportThe Indian journal of medical research2014
Enhanced care by community health workers in improving treatment adherence to antidepressant medication in rural women with major depression.
Trial report in The Indian journal of medical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 5 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Integrating Depression and Alcohol Use Care Into Primary Care in Low- and Middle-Income Countries: A Meta-Analysis.Psychiatric services (Washington, D.C.) · 2023Pooled it
- Interventions to promote medication adherence for chronic diseases in India: a systematic review.Frontiers in public health · 2023Pooled it
- Effectiveness of interventions to improve medication adherence in adults with depressive disorders: a meta-analysis.BMC psychiatry · 2022Pooled it
- Primary-level worker interventions for the care of people living with mental disorders and distress in low- and middle-income countries.The Cochrane database of systematic reviews · 2021Pooled it
- A Systematic Review of the Effectiveness of Treatments for Depression in Rural and Remote Residents.Clinical psychology & psychotherapyPooled it
- Understanding the role and organization of health workers delivering non-communicable disease management in primary care in low- and middle-income countries: a scoping review.BMC primary care · 2025Article
- Diversity in approaches in community-based mental health interventions in India: A narrative review and synthesis.Global mental health (Cambridge, England) · 2025Review
- Task-sharing for non-communicable disease prevention and control in low- and middle-income countries in the context of health worker shortages: A systematic review.PLOS global public health · 2025Article
- Types of Medication Non-adherence & Approaches to Enhance Medication Adherence in Mental Health Disorders: A Narrative Review.Indian journal of psychological medicine · 2024Review
- Mobile Mental Health in Women's Community-Based Organizations: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2023Article
- Successful ingredients of effective Collaborative Care programs in low- and middle-income countries: A rapid review.Global mental health (Cambridge, England) · 2023Review
- Interventions to increase help-seeking for mental health care in low- and middle-income countries: A systematic review.PLOS global public health · 2023Article
- Association between childhood trauma and medication adherence among patients with major depressive disorder: the moderating role of resilience.BMC psychiatry · 2022Article
- Embracing Technology for Capacity Building in Mental Health: New Path, Newer Challenges.The Psychiatric quarterly · 2021Article
- The effectiveness and cost-effectiveness of integrating mental health services in primary care in low- and middle-income countries: systematic review.BJPsych bulletin · 2021Article
- Can Mobile Health Improve Depression Treatment Access and Adherence Among Rural Indian Women? A Qualitative Study.Culture, medicine and psychiatry · 2020Article
- Effectiveness and cost-effectiveness of a multicomponent intervention to improve medication adherence in people with depressive disorders - MAPDep: a study protocol for a cluster randomized controlled trial.Patient preference and adherence · 2019Article
- Knowledge and Attitudes Towards Clinical Depression among Community Medical Providers in Gujarat, India.The Psychiatric quarterly · 2018Article
- Applying systems thinking to task shifting for mental health using lay providers: a review of the evidence.Global mental health (Cambridge, England) · 2017Review
- Author's response.The Indian journal of medical research · 2014Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectivesDepression remains largely undiagnosed in women residing in rural India and consequently many do not seek help. Moreover, among those who are diagnosed, many do not complete treatment due to high rates of attrition. This study was aimed to compare the effectiveness of enhanced care with usual care in improving treatment seeking and adherence to antidepressant medication in women with depression living in rural India.
methodsSix villages from rural Bangalore were randomized to either community health worker supported enhanced care or usual care. A total of 260 adult depressed women formed the final participants for the analysis. The outcome measures were number of women who sought and completed treatment, number of clinic visits, duration of treatment with antidepressant, changes in severity of depression (HDRS) and changes in quality of life [WHO-QOL (Brev) scale].
resultsA significantly greater number of women from the treatment intervention (TI) group completed the treatment and were on treatment for a longer duration compared to the treatment as usual (TAU) group. However, there were no significant differences in the severity of depression or quality of life between the TI and the TAU groups or between treatment completers and treatment dropouts at six months. INTERPRETATION &
conclusionsEnhanced care provided by the trained community health workers to rural women with major depression living in the community resulted in greater number of women seeking help and adhering to treatment with antidepressants. However, despite enhanced care a significant number of rural women diagnosed with depression either did not seek help or discontinued treatment prematurely. These findings have significant public health implications, as untreated depression is associated with considerable disability.
Indexed as
Identifiers
24718398PMC4001335W2121553441What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.