ArticlePloS one2014
Transcriptome analysis of integument differentially expressed genes in the pigment mutant (quail) during molting of silkworm, Bombyx mori.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 22 citations in OpenAlex.
- Molecular Characterization and RNA Interference Analysis of SLC26A10 FromFrontiers in physiology · 2022Article
- Comparative analysis of integument transcriptomes identifies genes that participate in marking pattern formation in three allelic mutants of silkworm, Bombyx mori.Functional & integrative genomics · 2020Article
- Comparative transcriptome analysis of Apis mellifera antennae of workers performing different tasks.Molecular genetics and genomics : MGG · 2018Article
- Genome-Wide Identification and Characterization of Fox Genes in the Honeybee,International journal of genomics · 2018Article
- Transcriptome analysis of the epidermis of the purple quail-like (q-lp) mutant of silkworm, Bombyx mori.PloS one · 2017Article
- BmncRNAdb: a comprehensive database of non-coding RNAs in the silkworm, Bombyx mori.BMC bioinformatics · 2016Article
- Transcriptome analysis of interactions between silkworm and cytoplasmic polyhedrosis virus.Scientific reports · 2016Article
- Positional cloning of a Bombyx pink-eyed white egg locus reveals the major role of cardinal in ommochrome synthesis.Heredity · 2016Article
- Transcriptomic Analysis of Resistant and Susceptible Bombyx mori Strains Following BmNPV Infection Provides Insights into the Antiviral Mechanisms.International journal of genomics · 2016Article
- Systematic Identification and Characterization of Long Non-Coding RNAs in the Silkworm, Bombyx mori.PloS one · 2016Article
- Functional Loss of Bmsei Causes Thermosensitive Epilepsy in Contractile Mutant Silkworm, Bombyx mori.Scientific reports · 2015Article
- Transcriptome analysis of shell color-related genes in the clam Meretrix meretrix.Marine biotechnology (New York, N.Y.) · 2015Article
- Identification of genes related to high royal jelly production in the honey bee (Apis mellifera) using microarray analysis.Genetics and molecular biologyArticle
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the silkworm Bombyx mori, pigment mutants with diverse body colors have been maintained throughout domestication for about 5000 years. The silkworm larval body color is formed through the mutual interaction of melanin, ommochromes, pteridines and uric acid. These pigments/compounds are synthesized by the cooperative action of various genes and enzymes. Previous reports showed that melanin, ommochrome and pteridine are increased in silkworm quail (q) mutants. To understand the pigment increase and alterations in pigment synthesis in q mutant, transcriptome profiles of the silkworm integument were investigated at 16 h after head capsule slippage in the fourth molt in q mutants and wild-type (Dazao). Compared to the wild-type, 1161 genes were differentially expressed in the q mutant. Of these modulated genes, 62.4% (725 genes) were upregulated and 37.6% (436 genes) were downregulated in the q mutant. The molecular function of differently expressed genes was analyzed by Blast2GO. The results showed that upregulated genes were mainly involved in protein binding, small molecule binding, transferase activity, nucleic acid binding, specific DNA-binding transcription factor activity and chromatin binding, while exclusively down-expressed genes functioned in oxidoreductase activity, cofactor binding, tetrapyrrole binding, peroxidase activity and pigment binding. We focused on genes related to melanin, pteridine and ommochrome biosynthesis; transport of uric acid; and juvenile hormone metabolism because of their importance in integument coloration during molting. This study identified differently expressed genes implicated in silkworm integument formation and pigmentation using silkworm q mutant. The results estimated the number and types of genes that drive new integument formation.
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