ArticlePloS one2014
Characterization of FLOWERING LOCUS T1 (FT1) gene in Brachypodium and wheat.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed, 154 citations in OpenAlex.
- Regulation of spikelet number during wheat spike development.bioRxiv : the preprint server for biology · 2026Article
- Optimizing Daily Light Integral in Seedling Stage Accelerates Heading and Flowering in Wheat Under LED Lighting.Plants (Basel, Switzerland) · 2026Article
- Fine-tuning wheat development for the winter to spring transition.Plant communications · 2025Article
- Enhancing genomic predictive ability of yield and yield-related traits in spring wheat by integrating major plant adaptation genes as a fixed effect.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Molecular genetic regulation of the vegetative-generative transition in wheat from an environmental perspective.Annals of botany · 2025Review
- Breeding potential of Spanish bread wheat landraces: genetic variability in vernalization and photoperiod sensitivity.Frontiers in plant science · 2025Article
- An eight-founder wheat MAGIC population allows fine-mapping of flowering time loci and provides novel insights into the genetic control of flowering time.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Natural alleles of LEAFY and WAPO1 interact to regulate spikelet number per spike in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- LEAFY and WAPO1 jointly regulate spikelet number per spike and floret development in wheat.Development (Cambridge, England) · 2024Article
- BdRCN4, a Brachypodium distachyon TFL1 homologue, is involved in regulation of apical meristem fate.Plant molecular biology · 2024Article
- Genome-wide evolutionary analysis of TKL_CTR1-DRK-2 gene family and functional characterization reveals that TaCTR1 positively regulates flowering time in wheat.BMC genomics · 2024Article
- Independent genetic factors control floret number and spikelet number inFrontiers in plant science · 2024Article
- Article
- Wheat bZIPC1 interacts with FT2 and contributes to the regulation of spikelet number per spike.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Sequencing 4.3 million mutations in wheat promoters to understand and modify gene expression.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- The Genomic Variation and Differentially Expressed Genes on the 6P Chromosomes in Wheat-International journal of molecular sciences · 2023Article
- A stress-inducible protein regulates drought tolerance and flowering time in Brachypodium and Arabidopsis.Plant physiology · 2023Article
- Integrated Genomic and Transcriptomic Elucidation of Flowering in Garlic.International journal of molecular sciences · 2022Article
- DNA hypermethylation promotes the flowering of orchardgrass during vernalization.Plant physiology · 2022Article
- Bacillus velezensis strain B26 modulates the inflorescence and root architecture of Brachypodium distachyon via hormone homeostasis.Scientific reports · 2022Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
The phase transition from vegetative to reproductive growth is a critical event in the life cycle of flowering plants. FLOWERING LOCUS T (FT) plays a central role in the regulation of this transition by integrating signals from multiple flowering pathways in the leaves and transmitting them to the shoot apical meristem. In this study, we characterized FT homologs in the temperate grasses Brachypodium distachyon and polyploid wheat using transgenic and mutant approaches. Downregulation of FT1 by RNAi was associated with a significant downregulation of the FT-like genes FT2 and FT4 in Brachypodium and FT2 and FT5 in wheat. In a transgenic wheat line carrying a highly-expressed FT1 allele, FT2 and FT3 were upregulated under both long and short days. Overexpression of FT1 caused extremely early flowering during shoot regeneration in both Brachypodium and hexaploid wheat, and resulted in insufficient vegetative tissue to support the production of viable seeds. Downregulation of FT1 transcripts by RNA interference (RNAi) resulted in non-flowering Brachypodium plants and late flowering plants (2-4 weeks delay) in wheat. A similar delay in heading time was observed in tetraploid wheat plants carrying mutations for both FT-A1 and FT-B1. Plants homozygous only for mutations in FT-B1 flowered later than plants homozygous only for mutations in FT-A1, which corresponded with higher transcript levels of FT-B1 relative to FT-A1 in the early stages of development. Taken together, our data indicate that FT1 plays a critical role in the regulation of flowering in Brachypodium and wheat, and that this role is associated with the simultaneous regulation of other FT-like genes. The differential effects of mutations in FT-A1 and FT-B1 on wheat heading time suggest that different allelic combinations of FT1 homoeologs could be used to adjust wheat heading time to improve adaptation to changing environments.
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