Evidence map›Paper›PMID 24717713›Full record

Trial reportPediatric dentistry

Dental sealants and flowable composite restorations and psychosocial, neuropsychological, and physical development in children.

Nancy N Maserejian, Peter Shrader, Felicia L Trachtenberg, Russ Hauser, David C Bellinger, Mary Tavares

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Pediatric dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Elution study of acrylic monomers from orthodontic materials using high performance liquid chromatography (HPLC).Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2022
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nancy N MaserejianSenior research scientist and an associate director, Department of Epidemiology, New England Research Institutes, Watertown, and Lecturer, Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, Mass., USA. nmaserej@post.harvard.edu.
Peter ShraderStatistician, and Massachusetts General Hospital, Boston, Mass., USA.
Felicia L TrachtenbergSenior statistician, New England Research Institutes, and Massachusetts General Hospital, Boston, Mass., USA.
Russ HauserProfessor, Harvard School of Public Health, Harvard Medical School, and Massachusetts General Hospital, Boston, Mass., USA.
David C BellingerProfessor, Harvard School of Public Health, Boston Children's Hospital, and Harvard Medical School, Boston, Mass., USA.
Mary TavaresProgram director, Advanced Graduate Education Program in Dental Public Health, Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, and a senior clinical investigator, The Forsyth Institute, Cambridge, Mass., USA.

Funding

HEALTH EFFECTS OF DENTAL AMALGAMS IN CHILDRENU01DE011886 · NIDCR · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, SONJA M · 1996 to 2005
$8.4M
Health Effects of Dental Composites in ChildrenR01ES019155 · NIEHS · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MASEREJIAN, NANCY NAIRI · 2011 to 2014
$946k
NIDCR NIH HHS U01 DE011886NIEHS NIH HHS R01 ES019155
6 · The paper itself

Abstract

purposeDental sealant materials may intraorally release their components, including bisphenol-A (BPA), but long-term health effects are uncertain. The New England Children's Amalgam Trial (NECAT) found that composite restorations were associated with psychosocial, but not neuropsychological or physical, outcomes. The previous analysis did not consider sealants and preventive resin restorations (PRRs), which were routinely placed. The purpose of this analysis was to examine sealant/PRR exposure in association with psychosocial and other health outcomes.

methodsNECAT recruited 534 six- to 10-year-olds and provided dental care during a five-year follow-up. Annually, examiners conducted psychosocial and neuropsychological tests and measured body mass index (BMI) and fat percentage (BF%). Associations between surface years (SY) of sealants/PRRs and outcomes were tested using multivariable models.

resultsCumulative exposure level to sealants and/or PRRs was not associated with psychosocial assessments (eg, total problems: Child Behavior Checklist, 10-SY β=-0.2 ± 0.3, P=.60) or neuropsychological tests (eg, full-scale IQ, 10-SY β=0.1 ± 0.2, P=.60). There were no associations for changes in BMI-for-age z-score (P=.40), BF% (girls 10-SY β=-0.2 ± 0.3; boys 10-SY β=-0.1 ± 0.3), or menarche (10-SY hazard ratio=0.91, 95% confidence interval=0.83-1.01, P=.08).

conclusionsThis study showed no associations between exposure level of dental sealants or PRRs and behavioral, neuropsychological, or physical development in children over 5-years.

Indexed as

Child BehaviorChild DevelopmentPsychology, ChildBisphenol A-Glycidyl MethacrylateBody Fat DistributionBody Mass IndexChildCohort StudiesCompomersComposite ResinsDental MaterialsDental Restoration, PermanentEnvironmental ExposureFemaleFollow-Up StudiesHumansBisphenol A-Glycidyl MethacrylateCompomersComposite ResinsDental MaterialsDyract Flow Compomerflowable hybrid compositePit and Fissure SealantsRevolution (composite resin)Silicon DioxideUltra Seal XTZ100 composite resinZirconium

Identifiers

PMID24717713
PMCPMC4854637

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.