Evidence map›Paper›PMID 24717141›Full record

ArticleJournal of addictive diseases2014

Association of alcohol use biomarkers and cognitive performance in veterans with problematic alcohol use and posttraumatic stress disorder: data from the mind your heart study.

Raj K Kalapatapu, Thomas C Neylan, Mathilda C Regan, Beth E Cohen

Abstract readMulticenter Study
In one paragraph

Article in Journal of addictive diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raj K Kalapatapua Department of Psychiatry , University of California , San Francisco , California , USA.
Thomas C Neylan
Mathilda C Regan
Beth E Cohen

Funding

Neuroendocrine Regulation of Sleep in PTSDR01MH073978 · NIMH · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI NEYLAN, THOMAS C · 2005 to 2008
$1.8M
OT-based Cognitive Rehabilitation of Cocaine AbusersK23DA034883 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KALAPATAPU, RAJKUMAR KIRAN · 2013 to 2017
$900k
Psychological Stress and Risk of Cardiovascular DiseaseK23HL094765 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COHEN, BETH · 2009 to 2013
$776k
Cognitive Behavioral Treatment of Insomnia in Posttraumatic Stress DisorderR34MH077667 · NIMH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI NEYLAN, THOMAS C · 2008 to 2010
$638k
NHLBI NIH HHS K23 HL094765NHLBI NIH HHS K23HL094765NIDA NIH HHS K23 DA034883NIDA NIH HHS K23DA034883NIMH NIH HHS 5R01MH073978-04NIMH NIH HHS R01 MH073978NIMH NIH HHS R34 MH077667
6 · The paper itself

Abstract

The authors conducted a study of alcohol use biomarkers and cognitive performance among 85 veterans with problematic alcohol use and posttraumatic stress disorder (PTSD). All analyses were adjusted for demographics, depression, anxiety, and PTSD symptoms. Elevated levels of aspartate aminotransferase were associated with worse performance on the Trail Making Test Part A and Hopkins Verbal Learning Test. Two other biomarkers were not associated with any neurocognitive measures. Indirect alcohol use biomarkers (e.g., aspartate aminotransferase) may have a specific role in identifying veterans with problematic alcohol use and PTSD who show a change in psychomotor speed and immediate verbal memory performance.

Indexed as

AdultAgedAlanine TransaminaseAlcohol-Related DisordersAspartate AminotransferasesBiomarkersCognitionErythrocyte IndicesFemaleHumansMaleMiddle AgedStress Disorders, Post-TraumaticVeteransAlanine TransaminaseAspartate AminotransferasesBiomarkersAlcohol use biomarkerscognitive performanceposttraumatic stress disorderproblematic alcohol use

Identifiers

PMID24717141
PMCPMC4071132

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.