ArticleVeterinary research2014
Perspectives of a scrapie resistance breeding scheme targeting Q211, S146 and K222 caprine PRNP alleles in Greek goats.
Article in Veterinary research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Silent Propagation of Classical Scrapie Prions in Homozygous KEmerging infectious diseases · 2025Article
- Article
- Polymorphisms of Codons 110, 146, 211 and 222 at the GoatAnimals : an open access journal from MDPI · 2021Article
- Goats naturally devoid of PrPVeterinary research · 2020Article
- Scrapie Control in EU Goat Population: Has the Last Gap Been Overcome?Frontiers in veterinary science · 2020Article
- Predicting the impact of selection for scrapie resistance on PRNP genotype frequencies in goats.Veterinary research · 2018Article
- Genetic profile of scrapie codons 146, 211 and 222 in the PRNP gene locus in three breeds of dairy goats.PloS one · 2018Article
- Genetic resistance to transmissible spongiform encephalopathies (TSE) in goats.EFSA journal. European Food Safety Authority · 2017Article
- Article
- Identification of amino acid variation in the prion protein associated with classical scrapie in Canadian dairy goats.BMC veterinary research · 2016Article
- Prion protein genotype survey confirms low frequency of scrapie-resistant K222 allele in British goat herds.The Veterinary record · 2016Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study investigates the potential use of the scrapie-protective Q211 S146 and K222 caprine PRNP alleles as targets for selective breeding in Greek goats. Genotyping data from a high number of healthy goats with special emphasis on bucks, revealed high frequencies of these alleles, while the estimated probabilities of disease occurrence in animals carrying these alleles were low, suggesting that they can be used for selection. Greek goats represent one of the largest populations in Europe. Thus, the considerations presented here are an example of the expected effect of such a scheme on scrapie occurrence and on stakeholders.
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Registered trials
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