Evidence map›Paper›PMID 24716140›Full record

ReviewJournal of traditional and complementary medicine2012

Chemical Constituents and Pharmacology of the Aristolochia ( mădōu ling) species.

Ping-Chung Kuo, Yue-Chiun Li, Tian-Shung Wu

Abstract readReview
In one paragraph

Review in Journal of traditional and complementary medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Biological Activities of Organic Extracts of the GenusMolecules (Basel, Switzerland) · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Plants (Basel, Switzerland) · 2024
    Article
  7. Overview of aristolochic acid nephropathy: an update.Kidney research and clinical practice · 2023
    Article
  8. Article
  9. Enhanced Production of Nitrogenated Metabolites with Anticancer Potential inInternational journal of molecular sciences · 2023
    Article
  10. Article
  11. Review
  12. Saudi journal of biological sciences · 2021
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Lignans and Their Derivatives from Plants as Antivirals.Molecules (Basel, Switzerland) · 2020
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ping-Chung KuoDepartment of Biotechnology, National Formosa University, Yunlin 632, Taiwan, ROC.
Yue-Chiun LiDepartment of Biotechnology, National Formosa University, Yunlin 632, Taiwan, ROC.
Tian-Shung WuDepartment of Chemistry, National Cheng Kung University, Tainan 701, Taiwan, ROC ; Department of Pharmacy, China Medical University, Taichung 404, Taiwan, ROC ; Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung 404, Taiwan, ROC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aristolochia ( mădōu ling) is an important genus widely cultivated and had long been known for their extensive use in traditional Chinese medicine. The genus has attracted so much great interest because of their numerous biological activity reports and unique constituents, aristolochic acids (AAs). In 2004, we reviewed the metabolites of Aristolochia species which have appeared in the literature, concerning the isolation, structural elucidation, biological activity and literature references. In addition, the nephrotoxicity of aristolochic acids, biosynthetic studies, ecological adaptation, and chemotaxonomy researches were also covered in the past review. In the present manuscript, we wish to review the various physiologically active compounds of different classes reported from Aristolochia species in the period between 2004 and 2011. In regard to the chemical and biological aspects of the constituents from the Aristolochia genus, this review would address the continuous development in the phytochemistry and the therapeutic application of the Aristolochia species. Moreover, the recent nephrotoxicity studies related to aristolochic acids would be covered in this review and the structure-toxicity relationship would be discussed.

Indexed as

AlkaloidAristolochiaAristolochic acidBioactivityFlavonoidTerpenoid

Identifiers

PMID24716140
PMCPMC3942903

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.