Evidence map›Paper›PMID 24715915›Full record

ArticleCase reports in medicine2014

One Patient, Two Uncommon B-Cell Neoplasms: Solitary Plasmacytoma following Complete Remission from Intravascular Large B-Cell Lymphoma Involving Central Nervous System.

Joycelyn Lee, Soo Yong Tan, Leonard H C Tan, Hwei Yee Lee, Khoon Leong Chuah, Tiffany Tang, Richard Quek, Kevin Tay, Miriam Tao, Soon Thye Lim and 1 more

Open access · goldAbstract read
In one paragraph

Article in Case reports in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Joycelyn LeeDepartment of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610.
Soo Yong TanDepartment of Pathology, Singapore General Hospital, 11 Jalan Tan Tock Seng, Singapore 169608.
Leonard H C TanDepartment of Pathology, Singapore General Hospital, 11 Jalan Tan Tock Seng, Singapore 169608.
Hwei Yee LeeDepartment of Pathology, Tan Tock Seng Hospital, Singapore 308433.
Khoon Leong ChuahDepartment of Pathology, Tan Tock Seng Hospital, Singapore 308433.
Tiffany TangDepartment of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610.
Richard QuekDepartment of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610.
Kevin TayDepartment of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610.
Miriam TaoDepartment of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610.
Soon Thye LimDepartment of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610.
Mohamad FaridDepartment of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610.
National Cancer Centre Singapore · SGTan Tock Seng Hospital · SGSingapore General Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Second lymphoid neoplasms are an uncommon but recognized feature of non-Hodgkin's lymphomas, putatively arising secondary to common genetic or environmental risk factors. Previous limited evaluations of clonal relatedness between successive mature B-cell malignancies have yielded mixed results. We describe the case of a man with intravascular large B-cell lymphoma involving the central nervous system who went into clinical remission following immunochemotherapy and brain radiation, only to relapse 2 years later with a plasmacytoma of bone causing cauda equina syndrome. The plasmacytoma stained strongly for the cell cycle regulator cyclin D1 on immunohistochemistry, while the original intravascular large cell lymphoma was negative, a disparity providing no support for clonal identity between the 2 neoplasms. Continued efforts atcataloging and evaluating unique associations of B-cell malignancies are critical to improving understanding of overarching disease biology in B-cell malignancies.

Identifiers

PMID24715915
PMCPMC3970463
OpenAlexW2011720479

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.