ArticleMolecular vision2014
Growth of the eye lens: I. Weight accumulation in multiple species.
Article in Molecular vision, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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Who cites it
28 citing papers in PubMed.
- State-of-the-Art Age Determination Methods for Amphibians and Reptiles.Animals : an open access journal from MDPI · 2025Review
- Biomechanical contributions to murine lens shape: Confinement, compaction, and residual stresses.Experimental eye research · 2025Article
- Oxidation-Induced Mixed Disulfide and Cataract Formation: A Review.Antioxidants (Basel, Switzerland) · 2025Review
- Comparative analysis of rodent lens morphometrics and biomechanical properties.Frontiers in ophthalmology · 2025Article
- Accounting for age: uncovering the nuanced drivers of mammal body-size responses to climate change.Journal of mammalogy · 2024Article
- Methodology Advances in Vertebrate Age Estimation.Animals : an open access journal from MDPI · 2024Review
- The significance of growth shells in development of symmetry, transparency, and refraction of the human lens.Frontiers in ophthalmology · 2024Review
- 3D visualization of cellular and molecular distributions in human crystalline lenses at different ages.American journal of translational research · 2024Article
- The effect of fibre cell remodelling on the power and optical quality of the lens.Journal of the Royal Society, Interface · 2023Article
- Discrete patterns of microbiome variability across timescales in a wild rodent population.BMC microbiology · 2023Article
- Insights into the biochemical and biophysical mechanisms mediating the longevity of the transparent optics of the eye lens.The Journal of biological chemistry · 2022Review
- Age-Related Retinal Changes in Wild-Type C57BL/6J Mice Between 2 and 32 Months.Investigative ophthalmology & visual science · 2021Article
- Keeping an eye on the use of eye-lens weight as a universal indicator of age for European wild rabbits.Scientific reports · 2021Article
- Three-dimensional data capture and analysis of intact eye lenses evidences emmetropia-associated changes in epithelial cell organization.Scientific reports · 2020Article
- Ultrahigh-Field Quantitative MR Microscopy of the Chicken Eye In Vivo Throughout the In Ovo Period.Molecular imaging and biology · 2019Article
- Article
- Brown Hare's (Lepus europaeus) Histone H1 Variant H1.2 as an Indicator of Anthropogenic Stress.Archives of environmental contamination and toxicology · 2018Article
- On the contribution of the nucleus and cortex to human lens shape and size.Clinical & experimental optometry · 2018Article
- Human lens weights with increasing age.Molecular vision · 2018Article
- The lens growth process.Progress in retinal and eye research · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
purposeTo examine the accumulation of wet and/or dry weight in the ocular lens as a function of age in different species.
methodsWet weights and/or fixed dry weights were obtained from measurements in the author's laboratory and from the literature for over 14,000 lenses of known-ages, representing 130 different species. Various algorithms were tested to determine the most suitable for describing the relationship between lens weight and age.
resultsFor 126 of the species examined, lens growth is continuous throughout life but asymptotic and can be reasonably described with a single logistic equation, W=Wm e(-(k/A)), where W is lens wet or dry weight; Wm is the maximum asymptotic weight, k is the logistic growth constant and A is the time from conception. For humans, elephants, hippopotami, minks, wild goats and woodchucks, lens growth appears to be biphasic. No gender differences could be detected in the lens weights for 70 species but male lenses are reportedly 10% larger than those of females in northern fur seals and pheasants. Dry weight accumulation is faster than that for wet weight in all species except birds and reptiles where the rates are the same. Low lens growth rates are associated with small animals with short gestation periods and short life spans.
conclusionsLens growth is continuous throughout life and, for most species, is independent of gender. For most, growth takes place through a monophasic asymptotic mode and is unaffected by events such as hibernation. This makes lens weight measurement a reliable tool for age determination of species culled in the wild. Compaction of the growing lens generates different properties, appropriate to an animal's lifestyle. How these events are controlled remains to be established.
Indexed as
Identifiers
24715758PMC3976689What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.