ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2014
Comparison of three commercially available softwares for measuring left ventricular perfusion and function by gated SPECT myocardial perfusion imaging.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
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- Reproducible Quantification of Regional Sympathetic Denervation with [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2020: positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Review
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2018. Part 1 of 2: Positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Review
- The effect of CT-based attenuation correction on the automatic perfusion score of myocardial perfusion imaging using a dedicated cardiac solid-state CZT SPECT/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Effect of patient positioning on the evaluation of myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Feasibility of biventricular volume and function assessment using first-pass gatedEJNMMI research · 2018Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology in 2017. Part 2 of 2: Myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Review
- Myocardial perfusion and left ventricular quantitative parameters obtained using gated myocardial SPECT: Comparison of three software packages.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Subacute cardiac rubidium-82 positron emission tomography (Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Towards Standardization of Quantitative Retinal Vascular Parameters: Comparison of SIVA and VAMPIRE Measurements in the Lothian Birth Cohort 1936.Translational vision science & technology · 2018Article
- Sources of variability in the measurement of perfusion defect size using commercially available software programs: Are there gender differences?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Left ventricular function in response to dipyridamole stress: head-to-head comparison betweenEuropean journal of nuclear medicine and molecular imaging · 2017Article
- Software-dependent processing variability in SPECT functional parameters: Clinical implications.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Serial imaging and outcome prediction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Review
- Review of cardiovascular imaging in The Journal of Nuclear Cardiology in 2014: Part 2 of 2: Myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Review
- Quantification of myocardial perfusion in clinical trials.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Call for a standard unit of defect size.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
- Cardiac volumes and left ventricular ejection fraction on myocardial perfusion scintigraphy.World journal of nuclear medicineArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe three softwares, Quantitative Perfusion SPECT (QPS), Emory Cardiac Toolbox, and 4 Dimension-Myocardial SPECT (4DM) are widely used with myocardial perfusion imaging (MPI) to determine perfusion defect size (PDS) and left ventricular (LV) function. There are limited data on the degree of agreement between these methods in quantifying the LV perfusion pattern and function. METHODS AND
resultsIn 120 consecutive patients who had abnormal regadenoson SPECT MPI with a visually derived summed stress score ≥4, the correlation between the softwares for measurements of PDS, reversible, and fixed defects was poor to fair (Spearman's ρ = 0.18-0.72). Overall, estimation of defect size was smaller by QPS and larger by 4DM. There was discordance among the softwares in 62% of the cases in defining PDS as small/moderate/large. The correlation between the softwares was better for measuring LVEF, volumes and mass (ρ = 0.84-0.97), and discrepant results for defining normal/mild-moderate/severe LV systolic dysfunction were prevalent in 28% of the patients.
conclusionThere are significant differences between the softwares in measuring PDS as well as LV function, and more importantly in defining small, moderate, or large ischemic burden. These results suggest the necessity of using the same software when assessing interval changes by serial imaging.
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