ReviewComprehensive Physiology2014
Vestibulo-sympathetic responses.
Review in Comprehensive Physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 102 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Study to Assess Sinusoidal Galvanic Vestibular Stimulation in Neurogenic Orthostatic Hypotension
Effects of Galvanic Vestibular Stimulation on Heart Rate Variability
Who cites it
102 citing papers in PubMed, 2 syntheses or guidelines pooled it, 160 citations in OpenAlex.
- A genome-wide meta-analysis uncovers six sequence variants conferring risk of vertigo.Communications biology · 2021Pooled it
- Natural History of Afferent Baroreflex Failure in Adults.Neurology · 2021Pooled it
- Long-term exposure to microgravity impairs vestibulo-cardiovascular reflex.Scientific reports · 2016Trial
- Repeated hypergravity training facilitates vestibular compensation associated with dorsal root ganglion remodeling.The journal of physiological sciences : JPS · 2026Article
- Polarity-Dependent Effects of Sinusoidal Galvanic Vestibular Stimulation on Cardiovascular Responses During Cognitive Load.Sensors (Basel, Switzerland) · 2026Article
- Review
- Ground-truth encoding of self-motion in the primate cerebellar nodulus and uvula.Nature communications · 2026Article
- Control of Blood Pressure Variability Across Behavioral States by Brainstem Adrenergic Neurons.Circulation research · 2026Article
- Association of Sarcopenia and Lower Bone Density With Positional Vertigo in the Morning: Insights From a Nationwide Survey.Journal of cachexia, sarcopenia and muscle · 2026Article
- Balance bridges upstream deficits associated with falls in older adults: evidence from the National Health and Aging Trends Study Round 13 cohort.Innovation in aging · 2026Article
- Toward a neuroergonomic understanding of spatial disorientation.Frontiers in physiology · 2026Review
- Case Report: Relief of long-standing severe motion sickness following stellate ganglion block.Frontiers in neuroscience · 2026Article
- Gastrointestinal motility in microgravity: a critical review of multi-level mechanisms and model-dependent effects.Frontiers in physiology · 2026Review
- The effect of complex double-axis rotation model on GABAergic neurons in caudal ventrolateral medulla of rats along the vestibulo-sympathetic reflex pathway.Frontiers in neuroanatomy · 2026Article
- Impact of barometric pressure on blood pressure during dialysis: Introducing intradialytic time-averaged cumulative systolic blood pressure (TACsBP-inD) as a new metric.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2025Article
- A wide-ranging review of galvanic vestibular stimulation: from its genesis to basic science and clinical applications.Experimental brain research · 2025Review
- The impact of vestibular-autonomic blood pressure responses derived from the head-up Tilt test on benign paroxysmal positional vertigo recurrence.Scientific reports · 2025Article
- Update on Clinical Physiology and Pathomechanisms for Vestibulo-Autonomic Interplay.Cerebellum (London, England) · 2025Review
- The vestibular system in pain and embodiment: cortical overlap, modulatory potential, and therapeutic perspectives.Frontiers in neuroscience · 2025Article
- The role of vestibular function on the vestibulo-sympathetic reflex recovery among children following moderate to severe traumatic brain injury.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Evidence accumulated over 30 years, from experiments on animals and human subjects, has conclusively demonstrated that inputs from the vestibular otolith organs contribute to the control of blood pressure during movement and changes in posture. This review considers the effects of gravity on the body axis, and the consequences of postural changes on blood distribution in the body. It then separately considers findings collected in experiments on animals and human subjects demonstrating that the vestibular system regulates blood distribution in the body during movement. Vestibulosympathetic reflexes differ from responses triggered by unloading of cardiovascular receptors such as baroreceptors and cardiopulmonary receptors, as they can be elicited before a change in blood distribution occurs in the body. Dissimilarities in the expression of vestibulosympathetic reflexes in humans and animals are also described. In particular, there is evidence from experiments in animals, but not humans, that vestibulosympathetic reflexes are patterned, and differ between body regions. Results from neurophysiological and neuroanatomical studies in animals are discussed that identify the neurons that mediate vestibulosympathetic responses, which include cells in the caudal aspect of the vestibular nucleus complex, interneurons in the lateral medullary reticular formation, and bulbospinal neurons in the rostral ventrolateral medulla. Recent findings showing that cognition can modify the gain of vestibulosympathetic responses are also presented, and neural pathways that could mediate adaptive plasticity in the responses are proposed, including connections of the posterior cerebellar vermis with the vestibular nuclei and brainstem nuclei that regulate blood pressure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.