ReviewMagnetic resonance in medicine2015
Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia.
Review in Magnetic resonance in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 1,341 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Molecular and Functional Basis of Successful Aging and Frailty
TRACK-TBI Precision Medicine Phase 2-Option I
Open Study of the Neurobiological Effects of Intranasal Ketamine in Children and Adults With Bipolar Disorder - Fear of Harm Phenotype
Longer-term Effects of Wild Blueberry Consumption on Brain Function in Older Men and Women
Who cites it
1,341 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- ESR Essentials: Perfusion MRI-practice recommendations by the European Society for Magnetic Resonance in Medicine and Biology.European radiology · 2026Guideline
- Arterial spin labeling MRI in patients undergoing carotid artery revascularization: a systematic review of the hemodynamic changes and clinical implications.European radiology · 2026Pooled it
- Arterial spin labeling MRI in assessing cerebral blood flow changes due to hypertension: a systematic review.Journal of hypertension · 2026Pooled it
- Meta-analysis of arterial spin labeling MRI to identify residual cerebral arteriovenous malformations after treatment.BMC medical imaging · 2025Pooled it
- Brain and physiological responses to flavored waters with different sweeteners: a randomized crossover study in healthy young adults.The American journal of clinical nutrition · 2026Trial
- Long-term effects of almond consumption on cognitive performance and brain vascular function: a randomized crossover trial in overweight/obese adults with prediabetes.European journal of clinical nutrition · 2026Trial
- Microvascular Function and Ambulatory Capacity in Peripheral Artery Disease.Circulation. Cardiovascular interventions · 2025Trial
- Cardiorespiratory fitness in relation to cerebral vascular and metabolic health in older adults with coronary artery disease.GeroScience · 2026Article
- Impact of MRI modality selection on glioma sub-region segmentation using 3D U-Net and Attention U-Net: A comparative evaluation across ten MRI sequences.European journal of radiology open · 2026Article
- Cognitive fatigue is related to reduced cerebral perfusion and sustained attention in patients with post COVID-19 condition: An fMRI study.Neuroimage. Reports · 2026Article
- Reference-Superimposed Reconstruction (RS-Recon) for Arterial Spin Labeling.Magnetic resonance in medicine · 2026Article
- Diagnostic value of 3D pCASL perfusion in glioma grading according to the WHO 2021 classification: a retrospective study of 530 cases.Neuroradiology · 2026Article
- MRI and proton MR spectroscopy in neonatal hypoxic-ischemic encephalopathy: a comprehensive imaging review.Japanese journal of radiology · 2026Review
- Regional oxygen extraction fraction is higher in older adults with type 2 diabetes and obesity: associations with cognition and metabolic markers.GeroScience · 2026Article
- Investigating molecular and hemodynamic effects of LSD in the human brain.Nature neuroscience · 2026Article
- Free-Breathing Arterial Spin Labeling MRI of the Kidney Using Flow-Sensitive-Alternating Inversion Recovery With Golden-Angle Radial Sampling.NMR in biomedicine · 2026Article
- Aging, brain network connectivity, and cognition: evidence from resting-state dynamic arterial spin labeling.NeuroImage · 2026Article
- Inter-Shot Motion Correction of Segmented 3D-GRASE ASL Perfusion Imaging With Self-Navigation and CAIPI.Magnetic resonance in medicine · 2026Article
- Denoising of ASL Data Using Deep Learning Priors Generated From Distribution Remapping.Magnetic resonance in medicine · 2026Article
- Neurovascular-metabolic coupling links hearing loss to cognitive impairment: Evidence from GABA and cerebral blood flow in presbycusis.Neurobiology of disease · 2026Article
1,281 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
This review provides a summary statement of recommended implementations of arterial spin labeling (ASL) for clinical applications. It is a consensus of the ISMRM Perfusion Study Group and the European ASL in Dementia consortium, both of whom met to reach this consensus in October 2012 in Amsterdam. Although ASL continues to undergo rapid technical development, we believe that current ASL methods are robust and ready to provide useful clinical information, and that a consensus statement on recommended implementations will help the clinical community to adopt a standardized approach. In this review, we describe the major considerations and trade-offs in implementing an ASL protocol and provide specific recommendations for a standard approach. Our conclusion is that as an optimal default implementation, we recommend pseudo-continuous labeling, background suppression, a segmented three-dimensional readout without vascular crushing gradients, and calculation and presentation of both label/control difference images and cerebral blood flow in absolute units using a simplified model.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.