ReviewAnnals of gastroenterology2011
Unraveling the link between leptin, ghrelin and different types of colitis.
Review in Annals of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Regulation of Intestinal Inflammation by Dietary Fats.Frontiers in immunology · 2020Pooled it
- Association Between Adipokines Levels with Inflammatory Bowel Disease (IBD): Systematic Reviews.Digestive diseases and sciences · 2017Pooled it
- Advancing Biomarker Discovery and Therapeutic Targets in Duchenne Muscular Dystrophy: A Comprehensive Review.International journal of molecular sciences · 2024Review
- Impact of Obesity on the Course of Management of Inflammatory Bowel Disease-A Review.Nutrients · 2022Review
- Role of the Ghrelin System in Colitis and Hepatitis as Risk Factors for Inflammatory-Related Cancers.International journal of molecular sciences · 2022Review
- Ghrelin and its role in gastrointestinal tract tumors (Review).Molecular medicine reports · 2021Review
- Role of Adipose Tissue in Inflammatory Bowel Disease.International journal of molecular sciences · 2021Review
- The Role of Adipose Tissue in the Pathogenesis and Therapeutic Outcomes of Inflammatory Bowel Disease.Cells · 2019Review
- TNF-α inhibits SCF, ghrelin, and substance P expressions through the NF-κB pathway activation in interstitial cells of Cajal.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2018Article
- Plasma ghrelin and leptin in patients with inflammatory bowel disease and its association with nutritional status.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptin and ghrelin are hormones with a tight inverse functional connection. Their inverse association is observed not only in the modulation of metabolism but also in the interaction with the immune system. A large number of studies have been launched regarding their association with various disorders, including different types of colitis. The majority of the available literature, however, focuses on inflammatory bowel disease. The role of leptin and ghrelin appears to be aggravating in most of these studies. Concerning intestinal infections, their levels seem to depend on the presence of certain species of micro-biota. As for models of ischemic and miscellaneous colitis, both hormones seem to act protectively, although evidence deriving from human studies is needed before any safe conclusions can be made. Conclusively, it seems that available data, from
Indexed as
Identifiers
24714276PMC3959465W2097170731What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.