Evidence map›Paper›PMID 24714139›Full record

ArticleAnnals of gastroenterology2012

Effects of

Mehmet Bektaş, Nurşen Saraç, Hülya Cetinkaya, Murat Törüner, Esra Erdemli, Onur Keskin, Irfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Ustün and 1 more

Open access · greenAbstract read
In one paragraph

Article in Annals of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Proton Pump Inhibitors and Fracture Risk: A Review of Current Evidence and Mechanisms Involved.International journal of environmental research and public health · 2019
    Review
  4. The differential diagnosis of Helicobacter pylori negative gastritis.Virchows Archiv : an international journal of pathology · 2018
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Mehmet BektaşDepartment of Gastroenterology (Mehmet Bektaş, Hülya Çetinkaya, Murat Törüner, Onur Keskin, İrfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Üstün, Kadir Bahar).
Nurşen SaraçDepartment of Histology and Embryology (Nurşen Saraç, Esra Erdemli), Ankara University School of Medicine.
Hülya CetinkayaDepartment of Gastroenterology (Mehmet Bektaş, Hülya Çetinkaya, Murat Törüner, Onur Keskin, İrfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Üstün, Kadir Bahar).
Murat TörünerDepartment of Gastroenterology (Mehmet Bektaş, Hülya Çetinkaya, Murat Törüner, Onur Keskin, İrfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Üstün, Kadir Bahar).
Esra ErdemliDepartment of Histology and Embryology (Nurşen Saraç, Esra Erdemli), Ankara University School of Medicine.
Onur KeskinDepartment of Gastroenterology (Mehmet Bektaş, Hülya Çetinkaya, Murat Törüner, Onur Keskin, İrfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Üstün, Kadir Bahar).
Irfan SoykanDepartment of Gastroenterology (Mehmet Bektaş, Hülya Çetinkaya, Murat Törüner, Onur Keskin, İrfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Üstün, Kadir Bahar).
Esen Ismet OktayDepartment of Gastroenterology (Mehmet Bektaş, Hülya Çetinkaya, Murat Törüner, Onur Keskin, İrfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Üstün, Kadir Bahar).
Esin KorkutDepartment of Gastroenterology (Mehmet Bektaş, Hülya Çetinkaya, Murat Törüner, Onur Keskin, İrfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Üstün, Kadir Bahar).
Yusuf UstünDepartment of Gastroenterology (Mehmet Bektaş, Hülya Çetinkaya, Murat Törüner, Onur Keskin, İrfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Üstün, Kadir Bahar).
Kadir BaharDepartment of Gastroenterology (Mehmet Bektaş, Hülya Çetinkaya, Murat Törüner, Onur Keskin, İrfan Soykan, Esen Ismet Oktay, Esin Korkut, Yusuf Üstün, Kadir Bahar).
Kainuun keskussairaala · FIDepartment of Embryology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExcessive release of gastrin leads to hypertrophy and hyperplasia of enterochromaffin-like cells (ECL) and prolonged stimulation of these cells causes functional impairment. The purpose of this study was to investigate the effect of

methodsFifteen patients who underwent endoscopy because of dyspeptic symptoms were enrolled in the present study. Biopsies were taken from corpus and antrum and existence of

resultsECL cells were completely normal in Group A. In group B, moderate hyperplasia and vacuolization was seen in ECL cells. In group C, ECL cell hyperplasia was observed and vacuoles with greater amounts of granules in enlarged vesicles were found more intensely in cytoplasm.

conclusionThe use of PPI for a long period of time and presence of

Indexed as

Enterochromaffin-like cellsHelicobacter pylori infectionproton pump inhibitors

Identifiers

PMID24714139
PMCPMC3959398
OpenAlexW2140573152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.