Trial reportJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2014
Ultrasound measurements of brain tissue pulsatility correlate with the volume of MRI white-matter hyperintensity.
Trial report in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07285928 (Contribution of Cerebral Pulsatility Assessment by Transcranial Ultrasound to the Decision-making for Cerebrospinal Fluid Shunting in Patients With Suspected Idiopathic Normal Pressure Hydrocephalus), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Contribution of Cerebral Pulsatility Assessment by Transcranial Ultrasound to the Decision-making for Cerebrospinal Fluid Shunting in Patients With Suspected Idiopathic Normal Pressure Hydrocephalus: a Prospective Cohort Study
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Magnetic resonance imaging of the pulsing brain: a systematic review.Magma (New York, N.Y.) · 2023Pooled it
- Brain Tissue Pulsatility is Increased in Midlife Depression: a Comparative Study Using Ultrasound Tissue Pulsatility Imaging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Trial
- Bringing neuroimaging to the bedside: can machine learning empower transcranial sonography?European radiology · 2026Article
- The pulsing brain: state of the art and an interdisciplinary perspective.Interface focus · 2025Review
- Article
- Physio-fUS: a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging.EBioMedicine · 2025Article
- Elevated brain pulsations in depression: insights from a pooled ultrasound cohort study.Interface focus · 2024Article
- A brief history of the development of transcranial tissue Doppler ultrasound.Interface focus · 2024Article
- Changes in cerebral connectivity and brain tissue pulsations with the antidepressant response to an equimolar mixture of oxygen and nitrous oxide: an MRI and ultrasound study.Molecular psychiatry · 2023Article
- Diagnostic Ability of Radiofrequency Ultrasound in Parkinson's Disease Compared to Conventional Transcranial Sonography and Magnetic Resonance Imaging.Diagnostics (Basel, Switzerland) · 2020Article
- The Effects of Hypocapnia on Brain Tissue Pulsations.Brain sciences · 2020Article
- Ultrasonic Assessment of the Medial Temporal Lobe Tissue Displacements in Alzheimer's Disease.Diagnostics (Basel, Switzerland) · 2020Article
- Ultrasound measurement of brain tissue movement in humans: A systematic review.Ultrasound (Leeds, England) · 2020Article
- Quantification of Endogenous Brain Tissue Displacement Imaging by Radiofrequency Ultrasound.Diagnostics (Basel, Switzerland) · 2020Article
- Anaesthetic management of a patient with a unique combination of anti-N-methyl-D-aspartate receptor encephalitis and stiff-person syndrome.BMJ case reports · 2018Article
- An Experimental Protocol for Assessing the Performance of New Ultrasound Probes Based on CMUT Technology in Application to Brain Imaging.Journal of visualized experiments : JoVE · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
White-matter hyperintensity (WMH) is frequently seen in magnetic resonance imaging (MRI), but the complete physiopathology of WMH remains to be elucidated. In this study, we sought to determine whether there is an association between the maximum brain tissue displacement (maxBTD), as assessed by ultrasound, and the WMH, as observed by MRI. Nine healthy women aged 60 to 85 years underwent ultrasound and MRI assessments. We found a significant negative correlation between maxBTD and WMH (ρ=-0.86, P<0.001), suggesting a link between cerebral hypoperfusion and WMH.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.