ArticleCancer research2014
Cancer stem cells: constantly evolving and functionally heterogeneous therapeutic targets.
Article in Cancer research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Erythroid Cells as Full Participants in the Tumor Microenvironment.International journal of molecular sciences · 2023Review
- Understanding and targeting prostate cancer cell heterogeneity and plasticity.Seminars in cancer biology · 2022Review
- Slow-cycling (dormant) cancer cells in therapy resistance, cancer relapse and metastasis.Seminars in cancer biology · 2022Review
- The Intratumoral Heterogeneity of Cancer Metabolism.Advances in experimental medicine and biology · 2021Article
- Radiotheranostic Targeting Cancer Stem Cells in Human Colorectal Cancer Xenografts.Molecular imaging and biology · 2020Article
- Heterogeneity of Tumors in Breast Cancer: Implications and Prospects for Prognosis and Therapeutics.Scientifica · 2020Review
- Novel Therapeutic Strategies for Ovarian Cancer Stem Cells.Frontiers in oncology · 2020Review
- NME1 Drives Expansion of Melanoma Cells with Enhanced Tumor Growth and Metastatic Properties.Molecular cancer research : MCR · 2019Article
- Nobiletin and Derivatives: Functional Compounds from Citrus Fruit Peel for Colon Cancer Chemoprevention.Cancers · 2019Review
- Scalable Culture Strategies for the Expansion of Patient-Derived Cancer Stem Cell Lines.Stem cells international · 2019Article
- The dualistic origin of human tumors.Seminars in cancer biology · 2018Review
- Gene expression profiling and construction of a putative gene regulatory network of bladder cancer tumor-initiating cells.Oncotarget · 2017Article
- The role of autophagy in the cross-talk between epithelial-mesenchymal transitioned tumor cells and cancer stem-like cells.Molecular cancer · 2017Review
- Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer.Cancer research · 2015Article
- Targeting tumor metastases: Drug delivery mechanisms and technologies.Journal of controlled release : official journal of the Controlled Release Society · 2015Review
- The challenge of targeting metastasis.Cancer metastasis reviews · 2015Review
- A biotherapy based on PSCs-in-3D spheroid-ameliorated biologics depletes in vivo cancer-sustaining stem cells.Oncotarget · 2015Article
- Androgen receptor and prostate cancer stem cells: biological mechanisms and clinical implications.Endocrine-related cancer · 2015Review
- Metabolic reprogramming: the emerging concept and associated therapeutic strategies.Journal of experimental & clinical cancer research : CR · 2015Review
- TLR9 signaling through NF-κB/RELA and STAT3 promotes tumor-propagating potential of prostate cancer cells.Oncotarget · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Elucidating the origin of and dynamic interrelationship between intratumoral cell subpopulations has clear clinical significance in helping to understand the cellular basis of treatment response, therapeutic resistance, and tumor relapse. Cancer stem cells (CSC), together with clonal evolution driven by genetic alterations, generate cancer cell heterogeneity commonly observed in clinical samples. The 2013 Shanghai International Symposium on Cancer Stem Cells brought together leaders in the field to highlight the most recent progress in phenotyping, characterizing, and targeting CSCs and in elucidating the relationship between the cell-of-origin of cancer and CSCs. Discussions from the symposium emphasize the urgent need in developing novel therapeutics to target the constantly evolving CSCs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.