Evidence map›Paper›PMID 24712816›Full record

ArticleThe Journal of chemical physics2014

Effect of charge patterns along a solid-state nanopore on polyelectrolyte translocation.

H H Katkar, M Muthukumar

Abstract read
In one paragraph

Article in The Journal of chemical physics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Pore shapes effects on polymer translocation.The European physical journal. E, Soft matter · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

H H KatkarDepartment of Polymer Science and Engineering, Room A212, University of Massachusetts, Amherst, Massachusetts 01003, USA.
M MuthukumarDepartment of Polymer Science and Engineering, Room A212, University of Massachusetts, Amherst, Massachusetts 01003, USA.

Funding

Modeling Macromolecular Transport through Protein Channels and NanoporesR01HG002776 · NHGRI · UNIVERSITY OF MASSACHUSETTS AMHERST · PI MUTHUKUMAR, MURUGAPPAN · 2003 to 2022
$5.3M
NHGRI NIH HHS R01 HG002776NHGRI NIH HHS R01HG002776-10
6 · The paper itself

Abstract

We investigate the effectiveness of charge patterns along a nanopore on translocation dynamics of a flexible polyelectrolyte. We perform a three dimensional Langevin dynamics simulation of a uniformly charged flexible polyelectrolyte translocating under uniform external electric field through a solid-state nanopore. We maintain the total charge along the pore to be constant, while varying its distribution by placing alternate charged and uncharged sections of different lengths along the pore length. Longest average translocation time is observed for a pattern corresponding to an optimum section length, with a major delay in the translocation time during the pore ejection stage. This optimum section length is independent of lengths of polyelectrolyte and pore within the range studied. A theory based on the Fokker-Planck formalism is found to successfully describe the observed trends with reasonable quantitative agreement.

Indexed as

MotionNanoporesComputer SimulationElectrolytesModels, ChemicalPolymersStatic ElectricityThermodynamicsElectrolytesPolymers

Identifiers

PMID24712816
PMCPMC3976468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.