Evidence map›Paper›PMID 24712687›Full record

ArticleInternational wound journal2016

Spinal cord stimulation to achieve wound healing in a primary lower limb critical ischaemia referral centre.

Giovanni De Caridi, Mafalda Massara, Antonio David, Massimiliano Giardina, Michele La Spada, Francesco Stilo, Francesco Spinelli, Raffaele Grande, Lucia Butrico, Stefano de Franciscis and 1 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in International wound journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06480786 (Spinal Cord Stimulation for Patients With Painful Diabetic Neuropathy and Peripheral Arterial Disease), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06480786 narecruitingnot on this mapstarted 2024, after this paper: background citation

Spinal Cord Stimulation for Patients With Painful Diabetic Neuropathy and Peripheral Arterial Disease: Mechanistic Insights From a Single-center, Randomized, Blinded, Sham-controlled Cross-over Proof-of-concept Trial

TypeinterventionalSponsorUniversity of NebraskaRan2024 to 2027Enrolled15ConditionsPeripheral Arterial Disease, Painful Diabetic Neuropathy, Diabetes Mellitus, Type 2, Chronic PainArmsSpinal cord stimulation, Sham stimulation
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Spinal Cord Stimulation for Intractable Chronic Limb Ischemia: A Narrative Review.Journal of cardiovascular development and disease · 2024
    Review
  4. Article
  5. Spinal cord stimulation may improve not only intractable pain but also necrotic wounds.Turkish journal of physical medicine and rehabilitation · 2018
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Giovanni De CaridiCardiovascular and Thoracic Department, "Policlinico G. Martino" Hospital, University of Messina, Messina, Italy.
Mafalda MassaraCardiovascular and Thoracic Department, "Policlinico G. Martino" Hospital, University of Messina, Messina, Italy.
Antonio DavidAnesthesiological Sciences Department, "Policlinico G. Martino" Hospital, University of Messina, Messina, Italy.
Massimiliano GiardinaAnesthesiological Sciences Department, "Policlinico G. Martino" Hospital, University of Messina, Messina, Italy.
Michele La SpadaCardiovascular and Thoracic Department, "Policlinico G. Martino" Hospital, University of Messina, Messina, Italy.
Francesco StiloCardiovascular and Thoracic Department, "Policlinico G. Martino" Hospital, University of Messina, Messina, Italy.
Francesco SpinelliCardiovascular and Thoracic Department, "Policlinico G. Martino" Hospital, University of Messina, Messina, Italy.
Raffaele GrandeDepartment of Surgical and Medical Science, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Lucia ButricoDepartment of Surgical and Medical Science, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Stefano de FranciscisDepartment of Surgical and Medical Science, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Raffaele SerraDepartment of Surgical and Medical Science, University Magna Graecia of Catanzaro, Catanzaro, Italy.
University of Messina · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critical lower limb ischaemia is a diffuse pathology that could cause claudication, severe ischaemic pain and tissue loss. The common treatment includes modification of risk factors, pharmacological therapy and endovascular or surgical revascularisation of the lower limb to restore a pulsatile flow distally. Spinal cord stimulator is seen as a valid alternative in patients unsuitable for revascularisation after endovascular or surgical revascularisation failure and as adjuvant therapy in the presence of a functioning bypass in patients with extensive tissue loss and gangrene presenting a slow and difficult wound healing. We report our experience on spinal cord stimulation (SCS) indication and implantation in patients with critical lower limb ischaemia, at a high-volume centre for the treatment of peripheral arterial disease.

Indexed as

Secondary Care CentersWound HealingFemaleFollow-Up StudiesHumansIschemiaLegMaleMiddle AgedRetrospective StudiesSpinal Cord StimulationTime FactorsTreatment OutcomeCritical lower limb ischaemiaPain reliefSpinal cord stimulationSurgical revascularisationWound healing

Identifiers

PMID24712687
PMCPMC7949687
OpenAlexW1514973990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.