ReviewImmunological reviews2014
Contextual functions of antigen-presenting cells in the gastrointestinal tract.
Review in Immunological reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- T Cell Responses to the Microbiota.Annual review of immunology · 2022Review
- Functional Analysis of the Transcriptional Regulator IκB-ζ in Intestinal Homeostasis.Digestive diseases and sciences · 2022Article
- Genetic and commensal induction of IL-18 drive intestinal epithelial MHCII via IFNγ.Mucosal immunology · 2021Article
- Reduction in the resident intestinal myelomonocytic cell population occurs duringOncology letters · 2021Article
- Strategies for Enhancement of Live-AttenuatedVaccines · 2021Review
- Tissue-Specific Immunity at the Oral Mucosal Barrier.Trends in immunology · 2018Review
- Resident macrophages in the healthy and inflamed intestinal muscularis externa.Pflugers Archiv : European journal of physiology · 2017Review
- Role of Dietary Metabolites in Regulating the Host Immune Response in Gastrointestinal Disease.Frontiers in immunology · 2017Review
- Anti-Inflammatory Effects of Vitamin D on Human Immune Cells in the Context of Bacterial Infection.Nutrients · 2016Article
- Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis.Scientific reports · 2016Article
- Making many from few: IL-12p40 as a model for the combinatorial assembly of heterodimeric cytokines.Cytokine · 2015Review
- Article
- Intestinal Monocyte-Derived Macrophages Control Commensal-Specific Th17 Responses.Cell reports · 2015Article
- Escaping Negative Selection: ILC You in the Gut.Immunity · 2015Article
- Microbiota metabolite regulation of host immune homeostasis: a mechanistic missing link.Current allergy and asthma reports · 2015Review
- Review
- Article
- Regulatory cells in health and disease.Immunological reviews · 2014Article
- The dichotomy of pathogens and allergens in vaccination approaches.Frontiers in microbiology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
The immune system of the gastrointestinal tract must be tightly regulated to limit pathologic responses toward innocuous antigens while simultaneously allowing for rapid development of effector responses against invading pathogens. Highly specialized antigen-presenting cell (APC) subsets present in the gut play a dominant role in balancing these seemingly disparate functions. In this review, we discuss new findings associated with the function of gut APCs and particularly the contextual role of these cells in both establishing tolerance to orally acquired antigens in the steady state and regulating acute inflammation during infection.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.