Evidence map›Paper›PMID 24712425›Full record

ReviewBiomarkers in medicine2014

γ-band abnormalities as markers of autism spectrum disorders.

Donald C Rojas, Lisa B Wilson

Abstract readReview
In one paragraph

Review in Biomarkers in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 3 syntheses or guidelines pooled it, 187 citations in OpenAlex.

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48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Donald C RojasDepartment of Psychology, Campus Delivery 1876, Colorado State University, Fort Collins, CO 80523, USA.
Lisa B Wilson
Colorado State University · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Development of Psychopathology, Psychobiology, & BehaviorT32MH015442 · NIMH · UNIVERSITY OF COLORADO DENVER · PI JASON R TREGELLAS · 1985 to 2026
$10.2M
NEUROSCIENCE TRAINING GRANTT32HD041697 · NICHD · UNIVERSITY OF COLORADO DENVER · PI RESTREPO, DIEGO · 2001 to 2015
$2.4M
Neuroscience Training GrantT32NS099042 · NINDS · UNIVERSITY OF COLORADO DENVER · PI Nidia Calero, GIDON S FELSEN · 2016 to 2026
$2.1M
Neural synchronydysfunction of gamma oscillations in autismR01MH082820 · NIMH · UNIVERSITY OF COLORADO DENVER · PI ROJAS, DONALD C. · 2010 to 2013
$1.2M
NICHD NIH HHS HD041697NICHD NIH HHS T32 HD041697NIMH NIH HHS MH015442NIMH NIH HHS MH082820NIMH NIH HHS R01 MH082820NIMH NIH HHS T32 MH015442NINDS NIH HHS T32 NS099042
6 · The paper itself

Abstract

Autism is a behaviorally diagnosed neurodevelopmental disorder with no current biomarkers with high specificity and sensitivity. γ-band abnormalities have been reported in many studies of autism spectrum disorders. γ-band activity is associated with perceptual and cognitive functions that are compromised in autism. Some γ-band deficits have also been seen in unaffected first-degree relatives, suggesting heritability of these findings. This review covers the published literature on γ abnormalities in autism, the proposed mechanisms underlying the deficits and the potential for translation into new treatments. Although the utility of γ-band metrics as diagnostic biomarkers is currently limited, such changes in autism are also useful as endophenotypes, for evaluating potential neural mechanisms, and for use as surrogate markers of treatment response to interventions.

Indexed as

BiomarkersChild Development Disorders, PervasiveElectroencephalographyHumansMagnetoencephalographyBiomarkers

Identifiers

PMID24712425
PMCPMC4105225
OpenAlexW2090724416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.